Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 14/20 | 0.81 |
| ▸ | L3MBTL1 | Q9Y468 | 11/20 | 0.81 |
| ▸ | L3MBTL4 | Q8NA19 | 2/20 | 0.71 |
| ▸ | HPGD | P15428 | 1/20 | 0.71 |
| ▸ | MBTD1 | Q05BQ5 | 6/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | TP53BP1 | Q12888 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23682802 | 0.90 | L3MBTL3 (1.00) | L3MBTL3L3MBTL1L3MBTL4MBTD1TP53BP1 | |
| SCHEMBL16573965 | 0.89 | HPGD (0.66) | L3MBTL3L3MBTL1HPGDMEN1KMT2A | |
| SCHEMBL1753626 | 0.85 | HPGD (0.97) | L3MBTL1HPGDMEN1KMT2A | |
| SCHEMBL23682749 | 0.84 | L3MBTL3 (1.00) | L3MBTL3L3MBTL1L3MBTL4MBTD1TP53BP1 | |
| SCHEMBL10174633 | 0.84 | HPGD (1.00) | L3MBTL1HPGDMEN1KMT2A | |
| SCHEMBL12969 | 0.84 | HPGD (1.00) | L3MBTL1HPGDMEN1KMT2A | |
| SCHEMBL19730382 | 0.83 | L3MBTL3 (1.00) | L3MBTL3L3MBTL1L3MBTL4HPGDMBTD1 | |
| SCHEMBL23682888 | 0.83 | L3MBTL3 (1.00) | L3MBTL3L3MBTL1L3MBTL4MBTD1TP53BP1 | |
| SCHEMBL14444078 | 0.83 | L3MBTL3 (0.75) | L3MBTL3L3MBTL1L3MBTL4MBTD1TP53BP1 | |
| SCHEMBL12977 | 0.82 | HPGD (0.69) | L3MBTL3L3MBTL1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247641-B2 | Compounds, derivatives, compositions, preparation and uses | MGI GP, INC. (US) | 2007-07-24 | — | — | US | disclosed |
| WO-2003014121-A9 | COMPOUNDS, DERIVATIVES, COMPOSITIONS, PREPARATION AND USES | GUILFORD PHARM INC (US) | 2004-03-25 | — | — | WO | disclosed |
| WO-2003014121-A1 | COMPOUNDS, DERIVATIVES, COMPOSITIONS, PREPARATION AND USES | GUILFORD PHARMACEUTICALS INC. (US) | 2003-02-20 | — | — | WO | disclosed |