Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 4/20 | 0.75 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 3/20 | 0.35 |
| ▸ | FNTB | P49356 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | DHPS | P49366 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3572398 | 0.92 | CYP11B2 (0.79) | CYP11B2CYP11B1CYP3A4TSHRHPGD | |
| Hydrochloric Acid SCHEMBL3572437 | 0.91 | CYP11B2 (0.78) | CYP11B2CYP11B1CYP3A4TSHRHPGD | |
| SCHEMBL3569027 | 0.89 | CYP11B1 (0.75) | CYP11B2CYP11B1CYP3A4TSHRHPGD | |
| Hydrochloric Acid SCHEMBL5229773 | 0.88 | CYP11B1 (0.74) | CYP11B2CYP11B1CYP3A4TSHRHPGD | |
| SCHEMBL5769986 | 0.87 | CYP11B1 (0.72) | CYP11B2CYP11B1CYP3A4ALDH1A1 | |
| SCHEMBL3574602 | 0.86 | CYP11B2 (1.00) | CYP11B2CYP11B1FNTAFNTBPGGT1B | |
| SCHEMBL3571246 | 0.83 | CYP11B2 (0.67) | CYP11B2CYP11B1CYP3A4FNTAPGGT1B | |
| SCHEMBL3574211 | 0.82 | CYP11B1 (0.66) | CYP11B2CYP11B1CYP3A4ALDH1A1MEN1 | |
| SCHEMBL3578304 | 0.82 | CYP11B2 (0.66) | CYP11B2CYP11B1CYP3A4TSHRHPGD | |
| Hydrochloric Acid SCHEMBL3574374 | 0.81 | CYP11B1 (0.65) | CYP11B2CYP11B1CYP3A4ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014914-A1 | ORGANIC COMPOUNDS AS AGENTS FOR THE TREATMENT OF ALDOSTERONE MEDIATED CONDITIONS | NOVARTIS AG (CH) | 2004-02-19 | — | — | WO | disclosed |