Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8354848 | 0.97 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL8358997 | 0.93 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL8356646 | 0.93 | PTGS2 (0.49) | PTGS2PTGS1 | |
| SCHEMBL8353887 | 0.93 | PTGS2 (0.69) | PTGS2PTGS1 | |
| SCHEMBL8359033 | 0.92 | LMNA (0.49) | PTGS2PTGS1 | |
| SCHEMBL8353575 | 0.91 | PTGS2 (0.60) | PTGS2PTGS1 | |
| SCHEMBL8356524 | 0.89 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL8356739 | 0.89 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL8359037 | 0.89 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL8361046 | 0.88 | PTGS2 (0.62) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877202-A | Indole derivatives useful to treat estrogen-related neoplasms and disorders | AVENTISUB II INC. | 1999-03-02 | — | — | US | claimed |
| US-5877202-A | Indole derivatives useful to treat estrogen-related neoplasms and disorders | AVENTISUB II INC. | 1999-03-02 | — | — | US | disclosed |