SCHEMBL8360792

SCHEMBL8360792

CC(C)(C)c1ccc2ccc(O)c(C(=O)O)c2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
HSD17B10 Q99714 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
MAPT P10636 3/20 0.44
GAA P10253 2/20 0.44
PKM P14618 1/20 0.44
RECQL P46063 1/20 0.44
SIRT1 Q96EB6 1/20 0.42
HSP90AA1 P07900 1/20 0.42
HSP90AB1 P08238 1/20 0.42
POLB P06746 2/20 0.42
PTPN5 P54829 1/20 0.42
CYP2D6 P10635 3/20 0.41
KDM4E B2RXH2 1/20 0.41
ATM Q13315 1/20 0.41
GLRA3 O75311 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6557124 0.89 ALDH1A1 (0.47) ALDH1A1HSD17B10TDP1HPGDALOX15
SCHEMBL11777345 0.84 GLRA3 (0.46) ALDH1A1HSD17B10TDP1HPGDALOX15
SCHEMBL8358274 0.83 CYP3A4 (0.45) MEN1KMT2AMAPTGAAHSP90AA1
SCHEMBL19196160 0.81 GLRA3 (0.42) ALDH1A1HSD17B10TDP1HPGDALOX15
SCHEMBL8358275 0.79 CNR1 (0.47)
SCHEMBL13573125 0.78 CA1 (0.50) ALDH1A1HSD17B10TDP1HPGDALOX15
SCHEMBL8360795 0.78 GLRA3 (0.46) ALDH1A1HSD17B10TDP1HPGDALOX15
SCHEMBL19201822 0.77 CSNK2A1 (0.53) ALDH1A1HSD17B10TDP1HPGDMEN1
SCHEMBL19195707 0.77 ALDH1A1 (0.57) ALDH1A1HSD17B10TDP1HPGDALOX15
SCHEMBL3388724 0.77 CA12 (0.50) ALDH1A1HSD17B10HPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11739223-B2 Surface primer compositions and methods of use ENVISTA (US) 2023-08-29 US disclosed
US-10696698-B2 Surface primer compositions and methods of use ORMCO CORPORATION 2020-06-30 US disclosed
US-20170217999-A1 SURFACE PRIMER COMPOSITIONS AND METHODS OF USE ORMCO CORPORATION 2017-08-03 US disclosed
US-20170217999-A1 SURFACE PRIMER COMPOSITIONS AND METHODS OF USE ORMCO CORPORATION 2017-08-03 US disclosed
US-5990332-A EXCELLENT IN CHARGE CONTROL OR CHARGE-ENHANCING PROPERTY, AND TONER FOR DEVELOPING ELECTROSTATIC IMAGES AND POWDERY PAINT FOR ELECTROSTATIC PAINTING ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 1999-11-23 US disclosed
US-5976749-A TONER FOR DEVELOPING ELECTROSTATIC IMAGES ORIENT CHEMICAL INDUSTRIES, LTD (JP) 1999-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10696698-B2 Surface primer compositions and methods of use SP1, GPER1, GRIN1 ALDH1A1 1177/4885HSD17B10 3466/4885TDP1 2998/4885
US-20170217999-A1 SURFACE PRIMER COMPOSITIONS AND METHODS OF USE SP1, GPER1, GRIN1 ALDH1A1 1177/4885HSD17B10 3466/4885TDP1 2998/4885
US-11739223-B2 Surface primer compositions and methods of use SP1, GPER1, GRIN1 ALDH1A1 1177/4885HSD17B10 3466/4885TDP1 2998/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.