SCHEMBL8360795

SCHEMBL8360795

CC(C)(C)c1cc(C(C)(C)C)c2ccc(O)c(C(=O)O)c2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLRA3 O75311 1/20 0.46
GLRB P48167 1/20 0.46
RARB P10826 2/20 0.38
RARG P13631 2/20 0.38
RXRA P19793 2/20 0.38
RXRB P28702 2/20 0.38
RXRG P48443 1/20 0.38
ALDH1A1 P00352 4/20 0.38
HSD17B10 Q99714 3/20 0.38
HPGD P15428 2/20 0.38
ALOX15 P16050 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
KDM4E B2RXH2 2/20 0.38
PTPN5 P54829 1/20 0.37
SIRT1 Q96EB6 1/20 0.37
CYP2C9 P11712 2/20 0.37
NR1I2 O75469 1/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8362063 0.79 SHBG (0.38) GLRA3GLRBALDH1A1HSD17B10ALOX15
SCHEMBL8360792 0.78 ALDH1A1 (0.48) GLRA3GLRBRARBRARGALDH1A1
SCHEMBL16147679 0.76 GLRA3 (0.55) GLRA3GLRBRARBRARGRXRA
SCHEMBL6557124 0.76 ALDH1A1 (0.47) GLRA3GLRBRARBRARGALDH1A1
SCHEMBL6466602 0.75 GLRA3 (0.57) GLRA3GLRBRARBRARGRXRA
SCHEMBL8362065 0.74 CNR2 (0.43)
SCHEMBL28419884 0.74 GLRA3 (0.55) GLRA3GLRBRARBRARGRXRA
SCHEMBL11564532 0.72 AKR1C2 (0.48) GLRA3GLRBRXRBALDH1A1HSD17B10
SCHEMBL14760909 0.72 GLRA3 (0.52) GLRA3GLRBRXRARXRBRXRG
SCHEMBL19196671 0.71 GLRA3 (0.49) GLRA3GLRBALDH1A1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5990332-A EXCELLENT IN CHARGE CONTROL OR CHARGE-ENHANCING PROPERTY, AND TONER FOR DEVELOPING ELECTROSTATIC IMAGES AND POWDERY PAINT FOR ELECTROSTATIC PAINTING ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 1999-11-23 US disclosed
US-5976749-A TONER FOR DEVELOPING ELECTROSTATIC IMAGES ORIENT CHEMICAL INDUSTRIES, LTD (JP) 1999-11-02 US disclosed