Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | BMP1 | P13497 | 2/20 | 0.49 |
| ▸ | MMP1 | P03956 | 4/20 | 0.48 |
| ▸ | MMP9 | P14780 | 4/20 | 0.48 |
| ▸ | MMP13 | P45452 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 2/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MMP7 | P09237 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8363842 | 0.95 | CNR1 (0.54) | CNR1CNR2BMP1MMP1MMP9 | |
| SCHEMBL8363828 | 0.91 | HDAC6 (0.44) | CNR1BMP1MAPTMEN1KMT2A | |
| SCHEMBL8360876 | 0.90 | KCNA5 (0.55) | CNR1CNR2BMP1MMP1MMP9 | |
| SCHEMBL8363144 | 0.89 | MEN1 (0.44) | MAPTMEN1KMT2ARORCALDH1A1 | |
| SCHEMBL8363942 | 0.89 | MMP1 (0.50) | CNR1CNR2BMP1MMP1MMP9 | |
| SCHEMBL8363147 | 0.88 | HDAC6 (0.46) | MAPTMEN1KMT2ASTSRORC | |
| SCHEMBL8363831 | 0.88 | CNR1 (0.48) | CNR1CNR2BMP1MMP1MMP9 | |
| SCHEMBL8363183 | 0.87 | CNR1 (0.49) | CNR1CNR2BMP1MMP1MMP9 | |
| SCHEMBL8363185 | 0.87 | MMP1 (0.47) | CNR1CNR2BMP1MMP1MMP9 | |
| SCHEMBL8363934 | 0.86 | MMP1 (0.48) | CNR1CNR2BMP1MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003013527-A1 | SULFONAMIDE DERIVATIVES AS GAMMA SECRETASE INHIBITORS | SCHERING CORPORATION (US) | 2003-02-20 | — | — | WO | disclosed |