SCHEMBL8361111

SCHEMBL8361111

O=C(O)c1ccc(C(=O)N(C2CCCCC2)C2CCCCC2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.68
KMT2A Q03164 2/20 0.68
KDM4E B2RXH2 1/20 0.68
MEN1 O00255 1/20 0.68
ALOX15 P16050 1/20 0.68
ALOX12 P18054 1/20 0.68
RECQL P46063 1/20 0.68
ADAM17 P78536 1/20 0.68
NPSR1 Q6W5P4 2/20 0.58
MAPT P10636 1/20 0.58
HTT P42858 1/20 0.58
HSD11B1 P28845 3/20 0.56
SRD5A2 P31213 1/20 0.50
S1PR1 P21453 2/20 0.49
ADORA2A P29274 1/20 0.48
SLC6A4 P31645 2/20 0.47
SLC6A2 P23975 1/20 0.46
SLC6A3 Q01959 1/20 0.46
AGER Q15109 3/20 0.46
MTNR1A P48039 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8361113 0.92 LMNA (0.77) LMNAKMT2AKDM4EMEN1ALOX15
SCHEMBL1004218 0.87 LMNA (0.65) LMNAKMT2AKDM4EMEN1ALOX15
SCHEMBL4486860 0.85 MEN1 (0.68) LMNAKMT2AKDM4EMEN1ALOX15
SCHEMBL4596398 0.85 LMNA (0.68) LMNAKMT2AKDM4EMEN1ALOX15
SCHEMBL2230652 0.85 SLC6A4 (0.62) LMNAKMT2AKDM4EMEN1ALOX15
SCHEMBL29539649 0.85 SLC6A4 (0.62) LMNAKMT2AKDM4EMEN1ALOX15
SCHEMBL9542146 0.84 LMNA (0.66) LMNAKMT2AKDM4EMEN1ALOX15
SCHEMBL9542160 0.84 MEN1 (0.71) LMNAKMT2AKDM4EMEN1ALOX15
SCHEMBL812387 0.84 LMNA (0.66) LMNAKMT2AKDM4EMEN1ALOX15
SCHEMBL9001814 0.84 LMNA (0.66) LMNAKMT2AKDM4EMEN1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0776933-B1 Polybutene-1 resin composition and a method of accelerating the crystal transformation NEW JAPAN CHEM CO LTD (JP) 1999-08-04 EP disclosed