Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.68 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8361113 | 0.92 | LMNA (0.77) | LMNAMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL4486860 | 0.85 | MEN1 (0.68) | LMNAMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL8361111 | 0.85 | LMNA (0.68) | LMNAMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL9542146 | 0.84 | LMNA (0.66) | LMNAMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL812387 | 0.84 | LMNA (0.66) | LMNAMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL9542160 | 0.84 | MEN1 (0.71) | LMNAMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL9001814 | 0.84 | LMNA (0.66) | LMNAMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL1004218 | 0.83 | LMNA (0.65) | LMNAMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL9540808 | 0.81 | LMNA (0.63) | LMNAMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL29051501 | 0.81 | LMNA (0.63) | LMNAMEN1KMT2AKDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685183-B1 | METHOD FOR PRODUCING CARBONYL REST-CONTAINING ORGANOSILICON COMPOUNDS | WACKER CHEMIE AG (DE) | 2008-01-16 | — | — | EP | disclosed |