SCHEMBL8361982

SCHEMBL8361982

NCC(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 6/20 0.49
NAALAD2 Q9Y3Q0 3/20 0.49
RIMKLA Q8IXN7 1/20 0.49
GNPAT O15228 2/20 0.43
EPHX2 P34913 1/20 0.39
GLO1 Q04760 1/20 0.39
BMP1 P13497 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8361988 1.00 FOLH1 (0.49) FOLH1NAALAD2RIMKLAGNPATEPHX2
SCHEMBL30261857 0.99 FOLH1 (0.47) FOLH1NAALAD2RIMKLAGNPATEPHX2
SCHEMBL29349975 0.94 FOLH1 (0.55) FOLH1NAALAD2RIMKLAGNPATEPHX2
SCHEMBL29630461 0.93 FOLH1 (0.41) FOLH1NAALAD2RIMKLAGNPATGLO1
SCHEMBL29742944 0.93 FOLH1 (0.47) FOLH1NAALAD2RIMKLAGNPATEPHX2
SCHEMBL31479995 0.93 FOLH1 (0.47) FOLH1NAALAD2RIMKLAGNPATEPHX2
SCHEMBL30078713 0.92 FOLH1 (0.53) FOLH1NAALAD2RIMKLAGNPATEPHX2
SCHEMBL29893926 0.92 FOLH1 (0.53) FOLH1NAALAD2RIMKLAGNPATEPHX2
SCHEMBL30974496 0.92 FOLH1 (0.44) FOLH1NAALAD2RIMKLAGNPATBMP1
SCHEMBL31522798 0.91 FOLH1 (0.43) FOLH1NAALAD2RIMKLAGNPATGLO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999040435-A1 PROTEIN FOLDING INHIBITORS NETZER WILLIAM J (US) 1999-08-12 WO disclosed