SCHEMBL29630461

SCHEMBL29630461

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nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 3/20 0.41
RIMKLA Q8IXN7 1/20 0.41
NAALAD2 Q9Y3Q0 1/20 0.41
QRFPR Q96P65 5/20 0.41
NMT2 O60551 1/20 0.39
NMT1 P30419 1/20 0.39
GNPAT O15228 1/20 0.38
TGFBR1 P36897 1/20 0.37
GLO1 Q04760 1/20 0.37
MME P08473 2/20 0.37
BMP1 P13497 1/20 0.36
PTGS1 P23219 1/20 0.36
GSTK1 Q9Y2Q3 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8361988 0.93 FOLH1 (0.49) FOLH1RIMKLANAALAD2GNPATGLO1
SCHEMBL8361982 0.93 FOLH1 (0.49) FOLH1RIMKLANAALAD2GNPATGLO1
SCHEMBL31522798 0.92 FOLH1 (0.43) FOLH1RIMKLANAALAD2QRFPRNMT2
SCHEMBL30496531 0.92 FOLH1 (0.43) FOLH1RIMKLANAALAD2QRFPRNMT2
SCHEMBL30261857 0.92 FOLH1 (0.47) FOLH1RIMKLANAALAD2GNPATGLO1
SCHEMBL29539031 0.91 QRFPR (0.43) QRFPRNMT2NMT1TGFBR1BMP1
SCHEMBL30261878 0.90 FOLH1 (0.47) FOLH1RIMKLANAALAD2QRFPRNMT2
SCHEMBL31479983 0.90 FOLH1 (0.43) FOLH1RIMKLANAALAD2QRFPRNMT2
SCHEMBL30139569 0.89 FOLH1 (0.45) FOLH1RIMKLANAALAD2QRFPRNMT2
SCHEMBL29824218 0.89 FOLH1 (0.45) FOLH1RIMKLANAALAD2QRFPRNMT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807899-B2 Biochemical reaction methods and reagents comprising intrinsically disordered regions Biocrucible Limited 2023-11-07 US disclosed
US-11344548-B2 Analogs of 3,5-dihydroxypentanoate for bone formation KAOHSIUNG MEDICAL UNIVERSITY (TW) 2022-05-31 US disclosed
US-20220145378-A1 BIOCHEMICAL REACTION METHODS AND REAGENTS COMPRISING INTRINSICALLY DISORDERED REGIONS Biocrucible Limited (GB) 2022-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11344548-B2 Analogs of 3,5-dihydroxypentanoate for bone formation CYP24A1, CYP27B1, CYP2R1 FOLH1 1578/4885RIMKLA 1215/4885NAALAD2 450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.