SCHEMBL29742944

SCHEMBL29742944

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nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 6/20 0.47
NAALAD2 Q9Y3Q0 3/20 0.47
RIMKLA Q8IXN7 1/20 0.47
GLO1 Q04760 1/20 0.43
PTGS1 P23219 1/20 0.43
GSTK1 Q9Y2Q3 1/20 0.43
GNPAT O15228 1/20 0.42
SLC15A2 Q16348 1/20 0.40
EPHX2 P34913 1/20 0.38
BMP1 P13497 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31479995 1.00 FOLH1 (0.47) FOLH1NAALAD2RIMKLAGLO1PTGS1
SCHEMBL31479983 0.95 FOLH1 (0.43) FOLH1NAALAD2RIMKLAGLO1PTGS1
SCHEMBL8361988 0.93 FOLH1 (0.49) FOLH1NAALAD2RIMKLAGLO1GNPAT
SCHEMBL8361982 0.93 FOLH1 (0.49) FOLH1NAALAD2RIMKLAGLO1GNPAT
SCHEMBL30099483 0.92 FOLH1 (0.59) FOLH1NAALAD2RIMKLAGLO1GNPAT
SCHEMBL30099577 0.92 FOLH1 (0.59) FOLH1NAALAD2RIMKLAGLO1GNPAT
SCHEMBL30261857 0.91 FOLH1 (0.47) FOLH1NAALAD2RIMKLAGLO1GNPAT
SCHEMBL30099613 0.91 FOLH1 (0.56) FOLH1NAALAD2RIMKLAGNPATSLC15A2
SCHEMBL30565198 0.91 FOLH1 (0.56) FOLH1NAALAD2RIMKLAGNPATSLC15A2
SCHEMBL32670748 0.90 GLO1 (0.49) FOLH1NAALAD2RIMKLAGLO1PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022136555-A9 IMPROVED CD30 TARGETING ANTIBODY DRUG CONJUGATES AND USES THEREOF LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) 2022-09-22 WO disclosed
US-20220193251-A1 CD30 TARGETING ANTIBODY DRUG CONJUGATES AND USES THEREOF LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) 2022-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220193251-A1 CD30 TARGETING ANTIBODY DRUG CONJUGATES AND USES THEREOF TUBB6, GALNT10, TUBB FOLH1 120/4885NAALAD2 219/4885RIMKLA 975/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.