⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3293711 | 0.83 | LMNA (0.46) | — | |
| SCHEMBL421475 | 0.78 | — | — | |
| SCHEMBL400262 | 0.77 | — | — | |
| SCHEMBL6927423 | 0.72 | LMNA (0.42) | — | |
| SCHEMBL15494056 | 0.72 | LMNA (0.42) | — | |
| SCHEMBL9548584 | 0.72 | LMNA (0.42) | — | |
| SCHEMBL9509880 | 0.70 | LMNA (0.40) | — | |
| SCHEMBL9979299 | 0.70 | LMNA (0.40) | — | |
| Bronopol SCHEMBL28857973 | 0.70 | LMNA (0.81) | — | |
| SCHEMBL7781961 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0373759-B1 | COMPOUND, COMPOSITION, PROCESS AND USE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-06-09 | — | — | EP | claimed |
| US-5112871-A | ANTI-MICROBIAL BROMO-NITRO COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-05-12 | — | — | US | claimed |
| EP-0373759-A1 | Compound, composition, process and use | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-20 | — | — | EP | claimed |
| JP-2193948-A | — | — | None | — | — | JP | disclosed |
| WO-1999045975-A1 | NON-WOVEN MATERIAL COMPRISING CYCLIC THIOHYDROXAMIC ACID | AVECIA LIMITED (GB) | 1999-09-16 | — | — | WO | disclosed |
| EP-0373759-B1 | COMPOUND, COMPOSITION, PROCESS AND USE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-06-09 | — | — | EP | disclosed |
| US-5112871-A | ANTI-MICROBIAL BROMO-NITRO COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-05-12 | — | — | US | disclosed |
| JP-H02193948-A | ANTI-MICROBIAL COMPOUND AND PRODUCTION THEREOF | IMPERIAL CHEM IND PLC <ICI> | 1990-07-31 | — | — | JP | disclosed |
| EP-0373759-A1 | Compound, composition, process and use | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-20 | — | — | EP | disclosed |