Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439253 | 0.89 | LMNA (0.44) | LMNAALDH1A1TDP1TSHR | |
| SCHEMBL2637043 | 0.83 | LMNA (0.39) | LMNAALDH1A1TDP1TSHR | |
| SCHEMBL8351999 | 0.79 | LMNA (0.50) | LMNAALDH1A1TDP1TSHRCA5A | |
| Nitric Acid SCHEMBL11103751 | 0.78 | ALDH1A1 (0.39) | LMNAALDH1A1TSHR | |
| SCHEMBL15494056 | 0.77 | LMNA (0.42) | LMNAALDH1A1TDP1TSHRCA5A | |
| SCHEMBL9548584 | 0.77 | LMNA (0.42) | LMNAALDH1A1TDP1TSHRCA5A | |
| SCHEMBL22312 | 0.75 | LMNA (0.52) | LMNAALDH1A1TDP1TSHRCA5A | |
| SCHEMBL9509880 | 0.74 | LMNA (0.40) | LMNAALDH1A1TDP1TSHRCA5A | |
| SCHEMBL9979299 | 0.74 | LMNA (0.40) | LMNAALDH1A1TDP1TSHRCA5A | |
| SCHEMBL3046216 | 0.73 | TSHR (0.42) | LMNAALDH1A1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0830326-A4 | HYDRAULIC CEMENT SET ACCELERATORS BASED ON NITROALCOHOLS | GRACE W R & CO (US) | 2003-03-26 | — | — | EP | disclosed |
| EP-0830326-A1 | HYDRAULIC CEMENT SET ACCELERATORS BASED ON NITROALCOHOLS | W.R. Grace & Co.-Conn. (US) | 1998-03-25 | — | — | EP | disclosed |
| WO-1996040597-A1 | HYDRAULIC CEMENT SET ACCELERATORS BASED ON NITROALCOHOLS | W.R. GRACE & CO.-CONN. (US) | 1996-12-19 | — | — | WO | disclosed |