Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethyl Maleate SCHEMBL8361901 | 0.87 | HCAR2 (0.38) | HCAR2 | |
| SCHEMBL1041602 | 0.81 | ODC1 (0.32) | CYP3A4 | |
| SCHEMBL27619457 | 0.76 | ATM (0.61) | HCAR2ATMCYP1A2MAPTCA12 | |
| Diethyl Maleate SCHEMBL8362165 | 0.74 | HCAR2 (0.40) | HCAR2ATMCYP1A2MAPTCA12 | |
| Diethyl Maleate SCHEMBL8362173 | 0.72 | HCAR2 (0.38) | HCAR2ATMCYP1A2MAPTCYP3A4 | |
| SCHEMBL1849033 | 0.71 | CYP3A4 (0.33) | CYP3A4 | |
| Diethyl Maleate SCHEMBL29034929 | 0.70 | ATM (0.69) | HCAR2ATMMAPTCA12CA1 | |
| SCHEMBL10414957 | 0.69 | HCAR2 (0.59) | HCAR2ATMCYP1A2MAPTCA12 | |
| SCHEMBL57181 | 0.68 | KIF11 (0.32) | FDPS | |
| Diethyl Maleate SCHEMBL8935022 | 0.68 | HCAR2 (0.76) | HCAR2ATMMAPTCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6001946-A | Curable silane-encapped compositions having improved performances | WITCO CORPORATION (US) | 1999-12-14 | — | — | US | disclosed |