SCHEMBL57181

SCHEMBL57181

COC([SiH3])(CCCN)OC

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.32
KCNH2 Q12809 1/20 0.32
FDPS P14324 1/20 0.30
PDE3A Q14432 1/20 0.30
NFKB1 P19838 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL56325 0.92 NFKB1 (0.35) FDPSNFKB1
SCHEMBL16892641 0.90 DNM1 (0.38) FDPSNFKB1
SCHEMBL28575057 0.90 DNM1 (0.38) FDPSNFKB1
SCHEMBL1041602 0.84 ODC1 (0.32)
SCHEMBL57611 0.83
SCHEMBL40404 0.80 CA12 (0.44)
SCHEMBL1978458 0.78
SCHEMBL11036494 0.78 CA12 (0.42)
Ammonia Solution, Strong SCHEMBL22712951 0.77 CA12 (0.41)
SCHEMBL6444276 0.77 CA12 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1535 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116478536-B Core-shell particle for toughening thermosetting resin, composite material and preparation method 吉林大学 2024-04-12 CN claimed
EP-4345121-A1 ANIONIC POLYMERIZATION OF SILOXANES Rudolf GmbH (DE) 2024-04-03 EP claimed
EP-4345120-A1 ANIONIC POLYMERIZATION OF SILOXANES Rudolf GmbH (DE) 2024-04-03 EP claimed
WO-2024021307-A1 PREPARATION METHOD FOR THERMALLY EXPANDABLE MICROSPHERES CONTAINING HYDROPHILIC ORGANIC MODIFIED COLLOIDAL SILICON DIOXIDE 万华化学集团股份有限公司 2024-02-01 WO claimed
US-11753564-B2 Cured siloxane coating and anticorrosion substrate formed therewith KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2023-09-12 US claimed
WO-2023139564-A1 ANTICORROSIVE COATING FOR METALS ARGOCHEM S.R.L. (IT) 2023-07-27 WO claimed
US-11708507-B1 Method for forming a sol-gel coating formulation KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2023-07-25 US claimed
CN-116478536-A Core-shell particle for toughening thermosetting resin, composite material and preparation method 吉林大学 2023-07-25 CN claimed
EP-4196513-A1 SELECTIVE POLYURETHANE PREPOLYMER SYNTHESIS PolyU GmbH (DE) 2023-06-21 EP claimed
US-20230066975-A1 CURED SILOXANE COATING AND ANTICORROSION SUBSTRATE FORMED THEREWITH KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2023-03-02 US claimed
US-20060162860-A1 Binding agents having barrier properties HENKEL AG & CO. KGAA (DE) 2006-07-27 US claimed
EP-1664226-A1 BINDING AGENTS HAVING BARRIER PROPERTIES Henkel Kommanditgesellschaft auf Aktien (DE) 2006-06-07 EP claimed
WO-2006042169-A2 POLYMER-BASED TISSUE-ADHESIVE FOR MEDICAL USE E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-04-20 WO claimed
US-20060079599-A1 Polymer-based tissue-adhesive form medical use ACTAMAX SURGICAL MATERIALS, LLC 2006-04-13 US claimed
WO-2006015659-A2 BONDING AGENT AND NANOPARTICLES WITH BARRIER PROPERTIES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-02-16 WO claimed
WO-2005033240-A1 BINDING AGENTS HAVING BARRIER PROPERTIES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2005-04-14 WO claimed
EP-0216007-B1 PROCESS FOR PRODUCING ORGANIC SILICON-TERMINATED POLYIMIDE PRECURSOR AND POLYIMIDE HITACHI, LTD. (JP) 1991-03-13 EP claimed
US-4748228-A Process for producing organic silicon-terminated polyimide precursor and polyimide HITACHI. LTD. (JP) 1988-05-31 US claimed
EP-0216007-A2 Process for producing organic silicon-terminated polyimide precursor and polyimide HITACHI, LTD. (JP) 1987-04-01 EP claimed
EP-0210444-A1 Vulcanizable silane-terminated polyurethane polymers UNION CARBIDE CORPORATION (US) 1987-02-04 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060079599-A1 Polymer-based tissue-adhesive form medical use ADSL, SI, VCAM1 KIF11 2237/4885KCNH2 4486/4885FDPS 3561/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.