Flutolanil

Flutolanil

SCHEMBL8362549

CC(C)Oc1cccc(NC(=O)c2ccccc2C(F)(F)F)c1.CC(C)Oc1cccc(NC(=O)c2ccccc2C(F)(F)F)c1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNK3 O14649 7/20 0.65
KCNK9 Q9NPC2 7/20 0.65
PTGS1 P23219 1/20 0.64
F2R P25116 1/20 0.61
RXFP1 Q9HBX9 3/20 0.59
PTPRC P08575 1/20 0.57
NPC1 O15118 2/20 0.54
RAB9A P51151 2/20 0.54
SLC1A3 P43003 1/20 0.53
SLC1A2 P43004 1/20 0.53
SLC1A1 P43005 1/20 0.53
MEN1 O00255 1/20 0.52
ALDH1A1 P00352 1/20 0.52
GAA P10253 1/20 0.52
MAPT P10636 1/20 0.52
ALOX12 P18054 1/20 0.52
CCR6 P51684 1/20 0.52
KMT2A Q03164 1/20 0.52
HTR2A P28223 1/20 0.52
TSPO P30536 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flutolanil SCHEMBL29451184 1.00 KCNK3 (0.65) KCNK3KCNK9PTGS1F2RRXFP1
Flutolanil SCHEMBL18555 1.00 KCNK3 (0.65) KCNK3KCNK9PTGS1F2RRXFP1
Flutolanil SCHEMBL18222334 0.94 KCNK3 (0.59) KCNK3KCNK9PTGS1F2RRXFP1
SCHEMBL11204897 0.88 NPC1 (0.70) KCNK3KCNK9PTGS1F2RRXFP1
SCHEMBL21652267 0.88 KCNK3 (0.56) KCNK3KCNK9PTGS1RXFP1NPC1
Flutolanil SCHEMBL28093924 0.86 KCNK3 (0.53) KCNK3KCNK9PTGS1F2RRXFP1
SCHEMBL11212635 0.85 KCNK3 (0.80) KCNK3KCNK9PTGS1F2RRXFP1
SCHEMBL3910254 0.84 KCNK3 (0.52) KCNK3KCNK9PTGS1F2RRXFP1
SCHEMBL9338889 0.83 KCNK3 (0.66) KCNK3KCNK9PTGS1F2RRXFP1
SCHEMBL16553649 0.83 KCNK3 (0.70) KCNK3KCNK9PTGS1F2RRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999026885-A1 COMPOSITIONS AND METHODS FOR ADSORPTION AND REMEDIATION OF ORGANIC COMPOUNDS UNIVERSITY OF FLORIDA (US) 1999-06-03 WO disclosed