SCHEMBL21652267

SCHEMBL21652267

CC(C)Oc1cccc(NC(=O)c2ccccc2C(C)(C)C)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNK3 O14649 7/20 0.56
KCNK9 Q9NPC2 7/20 0.56
NPC1 O15118 3/20 0.52
RAB9A P51151 3/20 0.52
KMT2A Q03164 3/20 0.51
MEN1 O00255 2/20 0.51
LMNA P02545 2/20 0.51
MAPT P10636 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
RXFP1 Q9HBX9 1/20 0.51
ALDH1A1 P00352 1/20 0.51
ALOX12 P18054 1/20 0.51
F2 P00734 1/20 0.50
PLG P00747 1/20 0.50
PLAU P00749 1/20 0.50
PLAT P00750 1/20 0.50
KLKB1 P03952 1/20 0.50
PRSS1 P07477 1/20 0.50
KDM4E B2RXH2 1/20 0.50
GAA P10253 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flutolanil SCHEMBL8362549 0.88 KCNK3 (0.65) KCNK3KCNK9NPC1RAB9AKMT2A
Flutolanil SCHEMBL18555 0.88 KCNK3 (0.65) KCNK3KCNK9NPC1RAB9AKMT2A
Flutolanil SCHEMBL29451184 0.88 KCNK3 (0.65) KCNK3KCNK9NPC1RAB9AKMT2A
Flutolanil SCHEMBL18222334 0.83 KCNK3 (0.59) KCNK3KCNK9KMT2AMEN1SMN1; SMN2
Mepronil SCHEMBL20522512 0.82 KCNK3 (0.67) KCNK3KCNK9NPC1RAB9AKMT2A
Mepronil SCHEMBL29453871 0.82 KCNK3 (0.67) KCNK3KCNK9NPC1RAB9AKMT2A
Mepronil SCHEMBL18447 0.82 KCNK3 (0.67) KCNK3KCNK9NPC1RAB9AKMT2A
Mepronil SCHEMBL30731287 0.82 KCNK3 (0.67) KCNK3KCNK9NPC1RAB9AKMT2A
SCHEMBL11587410 0.81 KMT2A (0.71) KCNK3KCNK9NPC1RAB9AKMT2A
SCHEMBL7667058 0.81 FADS1 (0.69) KCNK3KCNK9NPC1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10544092-B2 Malononitrile oxime ether compound and use thereof SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) 2020-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10544092-B2 Malononitrile oxime ether compound and use thereof ME1, MAL2, ME3 KCNK3 3092/4885KCNK9 2816/4885NPC1 4630/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.