SCHEMBL8362664

SCHEMBL8362664

OCCOc1ccc(/C(=C(/CCCl)c2ccccc2)c2ccc(O)cc2)cc1

nearest known ligand 0.79

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ ESR1 P03372 17/20 0.79
▸ CYP19A1 P11511 3/20 0.79
▸ ESR2 Q92731 2/20 0.79
▸ ESRRG P62508 16/20 0.74
▸ LMNA P02545 1/20 0.65
▸ HTR6 P50406 1/20 0.65
▸ ESRRB O95718 2/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8362672 1.00 ESR1 (0.79) ESR1CYP19A1ESR2ESRRGLMNA
SCHEMBL5738276 1.00 ESR1 (0.79) ESR1CYP19A1ESR2ESRRGLMNA
SCHEMBL5738281 1.00 ESR1 (0.79) ESR1CYP19A1ESR2ESRRGLMNA
SCHEMBL8362668 1.00 ESR1 (0.79) ESR1CYP19A1ESR2ESRRGLMNA
SCHEMBL5738427 1.00 ESR1 (0.79) ESR1CYP19A1ESR2ESRRGLMNA
SCHEMBL5737939 0.95 LMNA (0.71) ESR1CYP19A1ESR2ESRRGLMNA
Ospemifene SCHEMBL948118 0.95 LMNA (0.71) ESR1CYP19A1ESR2ESRRGLMNA
Ospemifene SCHEMBL2231997 0.95 LMNA (0.71) ESR1CYP19A1ESR2ESRRGLMNA
SCHEMBL8362689 0.95 ESR1 (0.70) ESR1CYP19A1ESR2ESRRGLMNA
SCHEMBL8362685 0.95 ESR1 (0.70) ESR1CYP19A1ESR2ESRRGLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114392276-B Anti-aging medicine prepared from improved anti-aging umbilical cord stem cells 河北意和医学检验实验室有限公司 2023-10-03 — — CN claimed
CN-114392276-A Anti-aging medicine prepared from improved anti-aging umbilical cord stem cells and related cosmetic products 北京岳淘生物科技有限公司 2022-04-26 — — CN claimed
CN-114392276-B Anti-aging medicine prepared from improved anti-aging umbilical cord stem cells 河北意和医学检验实验室有限公司 2023-10-03 — — CN disclosed
CN-114504598-B Application of umbilical cord stem cells in preparation of anti-aging drugs 前沿外泌体(珠海横琴)生物医药研发有限公司 2023-08-22 — — CN disclosed
CN-114504598-A Application of umbilical cord stem cells in preparation of anti-aging drugs and related beauty products 北京岳淘生物科技有限公司 2022-05-17 — — CN disclosed
CN-114392276-A Anti-aging medicine prepared from improved anti-aging umbilical cord stem cells and related cosmetic products 北京岳淘生物科技有限公司 2022-04-26 — — CN disclosed
US-8642079-B2 Solid formulations of ospemifene HORMOS MEDICAL CORPORATION (FI) 2014-02-04 — — US disclosed
US-8642079-B2 Solid formulations of ospemifene HORMOS MEDICAL CORPORATION (FI) 2014-02-04 — — US disclosed
EP-2286806-A1 Solid formulations of ospemifene Hormos Medical Ltd. (FI) 2011-02-23 — — EP disclosed
EP-0779808-B1 TRIPHENYLETHYLENES FOR THE PREVENTION AND TREATMENT OF OSTEOPOROSIS ORION YHTYMAE OY (FI) 1999-08-18 — — EP disclosed
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