Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 10/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5518748 | 0.85 | ESR1 (0.48) | ESR1ESR2ALOX15HSD17B10KDM4E | |
| SCHEMBL17083204 | 0.84 | ESR1 (0.64) | ESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL17075741 | 0.82 | ESR1 (0.65) | ESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL5509999 | 0.82 | ESR1 (0.40) | ESR1ESR2ALOX15HSD17B10KDM4E | |
| Betanaphthol SCHEMBL28305413 | 0.81 | CYP1A2 (0.59) | ESR1ESR2KDM4EALDH1A1MAPT | |
| SCHEMBL5513218 | 0.79 | ESR1 (0.41) | ESR1ESR2ALOX15HSD17B10HSD17B3 | |
| SCHEMBL7925571 | 0.78 | ESR1 (0.52) | ESR1ESR2ALOX15HSD17B10LMNA | |
| SCHEMBL30022727 | 0.78 | ESR1 (0.52) | ESR1ESR2ALOX15HSD17B10LMNA | |
| SCHEMBL31194916 | 0.77 | ESR1 (0.38) | ESR1ESR2ALOX15HSD17B10KDM4E | |
| SCHEMBL31323038 | 0.77 | ESR1 (0.45) | ESR1ESR2ALOX15HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9637466-B2 | Liquid crystal compound having 2, 6-difluorophenyl ether structure and liquid crystal composition thereof | DIC CORPORATION (JP) | 2017-05-02 | — | — | US | disclosed |
| US-9637466-B2 | Liquid crystal compound having 2, 6-difluorophenyl ether structure and liquid crystal composition thereof | DIC CORPORATION (JP) | 2017-05-02 | — | — | US | disclosed |
| US-9637466-B2 | Liquid crystal compound having 2, 6-difluorophenyl ether structure and liquid crystal composition thereof | DIC CORPORATION (JP) | 2017-05-02 | — | — | US | disclosed |
| CN-105308028-B | Liquid crystalline compound having 2, 6-difluorophenyl ether structure and liquid crystal composition thereof | DIC株式会社 | 2017-04-05 | — | — | CN | disclosed |
| US-9573923-B2 | Liquid crystal compound having 2, 6-difluorophenylether structure, and liquid crystal composition containing the same | DIC CORPORATION (JP) | 2017-02-21 | — | — | US | disclosed |
| US-9573923-B2 | Liquid crystal compound having 2, 6-difluorophenylether structure, and liquid crystal composition containing the same | DIC CORPORATION (JP) | 2017-02-21 | — | — | US | disclosed |
| US-9573923-B2 | Liquid crystal compound having 2, 6-difluorophenylether structure, and liquid crystal composition containing the same | DIC CORPORATION (JP) | 2017-02-21 | — | — | US | disclosed |
| US-20160159765-A1 | LIQUID CRYSTAL COMPOUND HAVING 2, 6-DIFLUOROPHENYLETHER STRUCTURE, AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | DIC CORPORATION (JP) | 2016-06-09 | — | — | US | disclosed |
| US-20160159765-A1 | LIQUID CRYSTAL COMPOUND HAVING 2, 6-DIFLUOROPHENYLETHER STRUCTURE, AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | DIC CORPORATION (JP) | 2016-06-09 | — | — | US | disclosed |
| US-20160159765-A1 | LIQUID CRYSTAL COMPOUND HAVING 2, 6-DIFLUOROPHENYLETHER STRUCTURE, AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | DIC CORPORATION (JP) | 2016-06-09 | — | — | US | disclosed |
| US-20140330045-A1 | COMPOUND HAVING 2-FLUOROPHENYLOXYMETHANE STRUCTURE | DIC CORPORATION (JP) | 2014-11-06 | — | — | US | disclosed |
| US-20140330045-A1 | COMPOUND HAVING 2-FLUOROPHENYLOXYMETHANE STRUCTURE | DIC CORPORATION (JP) | 2014-11-06 | — | — | US | disclosed |
| CN-103906727-A | Compound having 2-fluorophenyloxymethane structure | DAINIPPON INK & CHEMICALS | 2014-07-02 | — | — | CN | disclosed |
| WO-2014057780-A1 | COMPOUND HAVING FLUORINATED NAPHTHALENE STRUCTURE AND LIQUID CRYSTAL COMPOSITION OF SAID COMPOUND | DIC株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |
| CN-103717563-A | Compound with 2-fluorophenyloxymethane structure | DAINIPPON INK & CHEMICALS | 2014-04-09 | — | — | CN | disclosed |
| US-8129002-B2 | Compounds for use in liquid crystal media | MERCK PATENT GMBH (DE) | 2012-03-06 | — | — | US | disclosed |
| US-8129002-B2 | Compounds for use in liquid crystal media | MERCK PATENT GMBH (DE) | 2012-03-06 | — | — | US | disclosed |
| US-7531106-B2 | Mesogenic compounds, medium for electro-optical displays and electro-optical display | MERCK PATENT GMBH (DE) | 2009-05-12 | — | — | US | disclosed |
| US-7531106-B2 | Mesogenic compounds, medium for electro-optical displays and electro-optical display | MERCK PATENT GMBH (DE) | 2009-05-12 | — | — | US | disclosed |
| US-7425354-B2 | Photopolymerizable liquid crystal composition, its polymer or polymer composition, and optical compensation element | CHISSO CORPORATION (JP) | 2008-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140330045-A1 | COMPOUND HAVING 2-FLUOROPHENYLOXYMETHANE STRUCTURE | INF2, CFL1, CFD | ESR1 3566/4885ESR2 4385/4885ALOX15 1276/4885 |
| US-20160159765-A1 | LIQUID CRYSTAL COMPOUND HAVING 2, 6-DIFLUOROPHENYLETHER STRUCTURE, AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | FGFR2, FGFR1, FGF2 | ESR1 3184/4885ESR2 3816/4885ALOX15 2237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.