SCHEMBL8363

SCHEMBL8363

c1ccc2nnncc2c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.43
KDM4E B2RXH2 5/20 0.42
MAPT P10636 4/20 0.41
ALDH1A1 P00352 4/20 0.40
HPGD P15428 2/20 0.40
GLA P06280 1/20 0.40
ACHE P22303 1/20 0.40
NCF1 P14598 3/20 0.39
CYP1A2 P05177 3/20 0.39
NOS2 P35228 1/20 0.39
BACE1 P56817 1/20 0.39
CA12 O43570 1/20 0.39
CA9 Q16790 1/20 0.39
NQO2 P16083 1/20 0.39
GPR3 P46089 2/20 0.38
TP53 P04637 2/20 0.36
CYP3A4 P08684 2/20 0.36
GOT1 P17174 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
NPC1 O15118 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29663747 1.00 EGFR (0.43) EGFRKDM4EMAPTALDH1A1HPGD
SCHEMBL3184056 0.98 EGFR (0.41) EGFRKDM4EMAPTALDH1A1HPGD
Hydrochloric Acid SCHEMBL8610460 0.98 EGFR (0.41) EGFRKDM4EMAPTALDH1A1HPGD
Hydrochloric Acid SCHEMBL7423401 0.98 EGFR (0.41) EGFRKDM4EMAPTALDH1A1HPGD
Hydrazine SCHEMBL1594935 0.95 NCF1 (0.41) EGFRKDM4EMAPTALDH1A1HPGD
SCHEMBL28027351 0.93 EGFR (0.39) EGFRKDM4EMAPTALDH1A1HPGD
Formaldehyde SCHEMBL28737577 0.93 EGFR (0.39) EGFRKDM4EMAPTALDH1A1HPGD
Catechol SCHEMBL29102232 0.89 ALDH1A1 (0.40) EGFRKDM4EMAPTALDH1A1HPGD
Pyrrole SCHEMBL28694134 0.88 EGFR (0.35) EGFRKDM4EMAPTALDH1A1HPGD
Quinoline SCHEMBL28081711 0.86 ALDH1A1 (0.63) EGFRKDM4EMAPTALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5647 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119431397-B Benzotriazine free radical compound, preparation method thereof and application thereof in organic memristors and artificial synapses ZHENGZHOU UNIVERSITY (CN) 2026-05-26 CN claimed
WO-2026103686-A1 BICYCLIC COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF 上海宇道生物技术有限公司 2026-05-21 WO claimed
CN-122031406-A Orally disintegrating tablet and preparation method thereof 海南卫康制药(潜山)有限公司 2026-05-15 CN claimed
US-12532631-B2 Electronic apparatus and method of manufacturing the same SAMSUNG DISPLAY CO., LTD. (KR) 2026-01-20 US claimed
EP-4618758-A1 MIXTURES OF SUCCINATE DEHYDROGENASE INHIBITORS AND PICOLINAMIDES FMC Corporation (US) 2025-09-24 EP claimed
CN-119874631-A Synthesis method of 1,2, 3-benzotriazine-4-ketone 河北凯诺中星科技有限公司 2025-04-25 CN claimed
CN-119751462-A Benzotriazine diradical compound, preparation method and application thereof in organic resistive random access memory, near infrared detector and temperature control film 郑州大学 2025-04-04 CN claimed
CN-119751463-A Benzotriazine diradical compound, preparation method of compound and application of compound in solar interface evaporator 郑州大学 2025-04-04 CN claimed
US-20250089717-A1 FUNGICIDAL HALOMETHYL KETONES, HYDRATES AND ENOL ETHERS AND THEIR MIXTURES FMC CORP (US) 2025-03-20 US claimed
CN-119431397-A Benzotriazine free radical compound, preparation method thereof and application thereof in organic memristors and artificial synapses 郑州大学 2025-02-14 CN claimed
EP-0028660-B1 XANTHINOXYDASE INHIBITORS AND UTILIZATION OF BENZOTRIAZINE DERIVATIVES SIEGFRIED AKTIENGESELLSCHAFT (CH) 1985-10-23 EP claimed
EP-0154851-A1 Benzisoselenazolethiones,process for their preparation and pharmaceutical products containing these compounds A. Nattermann & Cie. GmbH (DE) 1985-09-18 EP claimed
EP-0078971-B1 REAGENT FOR THE DETERMINATION OF GLUCOSE IN BIOLOGICAL FLUIDS BEHRINGWERKE Aktiengesellschaft (DE) 1985-03-27 EP claimed
EP-0024931-B1 1,2,4-BENZOTRIAZINYLAMINOPHENOXYALKANE CARBOXYLIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES ICI AUSTRALIA LIMITED (AU) 1984-10-17 EP claimed
EP-0024932-B1 1,2,4-BENZOTRIAZINYLOXYPHENOXYALKANE CARBOXYLIC-ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION, THEIR USE AS HERBICIDES, AND THEIR PREPARATION ICI AUSTRALIA LIMITED (AU) 1984-08-01 EP claimed
EP-0100899-A2 Benzisoselenazolones, process for their preparation and pharmaceutical compositions containing them A. Nattermann & Cie. GmbH (DE) 1984-02-22 EP claimed
EP-0078971-A1 Reagent for the determination of glucose in biological fluids BEHRINGWERKE Aktiengesellschaft (DE) 1983-05-18 EP claimed
US-4343660-A PETROLEUM SULFONATE AND COMPLEXING AGENT, FOR COPPER CABLES PETROLITE CORPORATION (US) 1982-08-10 US claimed
EP-0024932-A2 1,2,4-Benzotriazinyloxyphenoxyalkane carboxylic-acid derivatives, processes for their preparation, their use as herbicides, and their preparation ICI AUSTRALIA LIMITED (AU) 1981-03-11 EP claimed
EP-0024931-A2 1,2,4-Benzotriazinylaminophenoxyalkane carboxylic acid derivatives, processes for their preparation and their use as herbicides ICI AUSTRALIA LIMITED (AU) 1981-03-11 EP claimed