Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8356786 | 0.91 | TSHR (0.42) | TSHRPOLBALOX15AGTR1AGTR2 | |
| SCHEMBL8361928 | 0.89 | TSHR (0.38) | TSHRPOLBALOX15AGTR1AGTR2 | |
| SCHEMBL8359361 | 0.88 | TSHR (0.38) | TSHRPOLBALOX15AGTR1AGTR2 | |
| SCHEMBL8359917 | 0.84 | TSHR (0.36) | TSHRPOLBALOX15 | |
| SCHEMBL8359640 | 0.83 | TSHR (0.35) | TSHRPOLBALOX15PLA2G2A | |
| SCHEMBL8364566 | 0.82 | TSHR (0.35) | TSHRPOLBALOX15TLR8 | |
| SCHEMBL8362004 | 0.81 | MAPK1 (0.45) | TSHRALOX15AGTR1AGTR2TLR8 | |
| SCHEMBL8364350 | 0.76 | TSHR (0.38) | TSHRPOLBALOX15 | |
| SCHEMBL8505356 | 0.75 | AGTR2 (0.35) | AGTR2 | |
| SCHEMBL8362081 | 0.75 | AGTR2 (0.36) | AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883111-A | STRONG AND LONG-LASTING ACTION BY ORAL ADMINISTRATION; HYPOTENSIVE AGENTS; CARDIOTONIC AGENTS; ALZHEIMER'S DISEASE; | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-03-16 | — | — | US | disclosed |