Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8421434 | 0.86 | RXFP1 (0.36) | — | |
| SCHEMBL8505253 | 0.86 | MAPT (0.32) | AGTR2 | |
| SCHEMBL8362081 | 0.85 | AGTR2 (0.36) | AGTR2 | |
| SCHEMBL8419029 | 0.85 | AGTR1 (0.37) | AGTR2 | |
| SCHEMBL8421711 | 0.85 | AGTR1 (0.41) | AGTR2 | |
| SCHEMBL8421733 | 0.85 | ALDH1A1 (0.35) | — | |
| SCHEMBL8417991 | 0.85 | ALOX15 (0.34) | — | |
| SCHEMBL8362111 | 0.85 | AGTR2 (0.34) | AGTR2 | |
| SCHEMBL8418031 | 0.84 | ABCB11 (0.34) | AGTR2 | |
| SCHEMBL8417950 | 0.84 | ALOX15 (0.35) | AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889036-A | ADMINISTERING 2-ETHOXY-1-((2'-(4,5-DIHYDRO-5-OXO-1,2,4-OXADIAZOL-3-YL)-BIPHE NYL)METHYL-1H-BENZIMIDAZOL-7-CARBOXYLIC ACID | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-03-30 | — | — | US | disclosed |