Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | BMP1 | P13497 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8364244 | 0.91 | HDAC6 (0.44) | CNR1HDAC6MEN1KMT2AHDAC8 | |
| SCHEMBL8364401 | 0.90 | HDAC6 (0.44) | CNR1HDAC6MEN1KMT2AHDAC8 | |
| SCHEMBL8364256 | 0.90 | HDAC6 (0.46) | CNR1HDAC6MEN1KMT2AHDAC8 | |
| SCHEMBL8361728 | 0.90 | RORC (0.51) | CNR1HDAC6MEN1KMT2AHDAC8 | |
| SCHEMBL8361739 | 0.89 | HDAC6 (0.46) | CNR1HDAC6MEN1KMT2AHDAC8 | |
| SCHEMBL8364250 | 0.89 | KMT2A (0.47) | CNR1HDAC6MEN1KMT2AHDAC8 | |
| SCHEMBL8363852 | 0.88 | ALOX15 (0.47) | CNR1HDAC6MEN1KMT2AHDAC8 | |
| SCHEMBL8364382 | 0.88 | CNR1 (0.49) | CNR1HDAC6MEN1KMT2AHDAC8 | |
| SCHEMBL8361730 | 0.87 | RORC (0.46) | CNR1HDAC6MEN1KMT2AHDAC8 | |
| SCHEMBL8363828 | 0.87 | HDAC6 (0.44) | CNR1HDAC6MEN1KMT2AHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003013527-A1 | SULFONAMIDE DERIVATIVES AS GAMMA SECRETASE INHIBITORS | SCHERING CORPORATION (US) | 2003-02-20 | — | — | WO | disclosed |