Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 16/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8364455 | 0.90 | BDKRB2 (0.60) | BDKRB2MAPTTHRBALDH1A1HPGD | |
| SCHEMBL7666017 | 0.89 | BDKRB2 (0.62) | BDKRB2MAPTTHRBALDH1A1HPGD | |
| SCHEMBL8361700 | 0.84 | BDKRB2 (0.57) | BDKRB2MAPTTHRBALDH1A1LMNA | |
| SCHEMBL8361842 | 0.82 | BDKRB2 (0.66) | BDKRB2 | |
| SCHEMBL6641880 | 0.81 | BDKRB2 (0.57) | BDKRB2MAPTTHRBLMNAPOLB | |
| SCHEMBL8366115 | 0.81 | BDKRB2 (0.61) | BDKRB2 | |
| SCHEMBL8364497 | 0.81 | BDKRB2 (0.61) | BDKRB2 | |
| SCHEMBL4600378 | 0.81 | BDKRB2 (0.63) | BDKRB2 | |
| SCHEMBL8367963 | 0.80 | BDKRB2 (0.54) | BDKRB2 | |
| SCHEMBL8367361 | 0.80 | BDKRB2 (0.63) | BDKRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994368-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, ANALGESICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| EP-0807105-A1 | PYRIDOPYRIMIDONES, QUINOLINES AND FUSED N-HERETOCYCLES AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-19 | — | — | EP | disclosed |
| WO-1996013485-A1 | PYRIDOPYRIMIDONES, QUINOLINES AND FUSED N-HERETOCYCLES AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-09 | — | — | WO | disclosed |