SCHEMBL8366115

SCHEMBL8366115

Cc1ccc2cccc(OCc3c(Cl)ccc(NC(=O)NCC(=O)O)c3Cl)c2n1

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BDKRB2 P30411 17/20 0.61
PTGDR2 Q9Y5Y4 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8367361 0.90 BDKRB2 (0.63) BDKRB2
SCHEMBL8364497 0.90 BDKRB2 (0.61) BDKRB2
SCHEMBL7666017 0.85 BDKRB2 (0.62) BDKRB2
SCHEMBL8367963 0.84 BDKRB2 (0.54) BDKRB2
SCHEMBL8953762 0.83 BDKRB2 (0.63) BDKRB2
SCHEMBL8364455 0.82 BDKRB2 (0.60) BDKRB2
SCHEMBL8367962 0.82 BDKRB2 (0.68) BDKRB2
SCHEMBL8364296 0.81 BDKRB2 (0.59) BDKRB2
SCHEMBL4600378 0.81 BDKRB2 (0.63) BDKRB2
SCHEMBL8364514 0.80 BDKRB2 (0.57) BDKRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5994368-A ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, ANALGESICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-11-30 US disclosed
EP-0807105-A1 PYRIDOPYRIMIDONES, QUINOLINES AND FUSED N-HERETOCYCLES AS BRADYKININ ANTAGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-11-19 EP disclosed
WO-1996013485-A1 PYRIDOPYRIMIDONES, QUINOLINES AND FUSED N-HERETOCYCLES AS BRADYKININ ANTAGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-05-09 WO disclosed