Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 11/20 | 0.69 |
| ▸ | MMP13 | P45452 | 11/20 | 0.69 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 3/20 | 0.42 |
| ▸ | MMP8 | P22894 | 3/20 | 0.42 |
| ▸ | MMP12 | P39900 | 3/20 | 0.42 |
| ▸ | MMP14 | P50281 | 3/20 | 0.42 |
| ▸ | MMP16 | P51512 | 3/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5898933 | 0.81 | MMP2 (1.00) | MMP2MMP13HDAC6MMP3 | |
| SCHEMBL5899024 | 0.80 | MMP2 (1.00) | MMP2MMP13MEN1KMT2A | |
| SCHEMBL5898936 | 0.77 | KMT2A (0.45) | MMP2MMP13KMT2A | |
| SCHEMBL12150842 | 0.76 | MMP2 (0.69) | MMP2MMP13HDAC3HDAC4HDAC1 | |
| SCHEMBL5898957 | 0.74 | MMP2 (1.00) | MMP2MMP13 | |
| SCHEMBL7072376 | 0.74 | MMP2 (0.61) | MMP2MMP13FAAHMEN1KMT2A | |
| SCHEMBL7074343 | 0.73 | MMP2 (0.76) | MMP2MMP13FAAH | |
| SCHEMBL5898931 | 0.73 | MMP2 (0.76) | MMP2MMP13KMT2A | |
| SCHEMBL5898968 | 0.72 | MMP2 (0.63) | MMP2MMP13 | |
| SCHEMBL8364732 | 0.72 | MMP2 (0.59) | MMP2MMP13HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007954-A2 | SULFONYL ARYL HYDROXAMATES AND THEIR USE AS MATRIX METALLOPROTEASE INHIBITORS | PHARMACIA CORPORATION (US) | 2003-01-30 | — | — | WO | disclosed |