Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL15053704 | 0.95 | CA2 (0.39) | CA2SLC34A1KDM4EMMP2THRB | |
| Phosphoric Acid SCHEMBL28745250 | 0.95 | CA2 (0.39) | CA2SLC34A1KDM4EMMP2THRB | |
| Phosphoric Acid SCHEMBL814222 | 0.95 | — | — | |
| Phosphoric Acid SCHEMBL10896983 | 0.95 | CA2 (0.39) | CA2SLC34A1KDM4EMMP2THRB | |
| Phosphoric Acid SCHEMBL15488014 | 0.91 | CA2 (0.36) | CA2SLC34A1KDM4EMMP2THRB | |
| Phosphoric Acid SCHEMBL30371992 | 0.91 | CA2 (0.36) | CA2SLC34A1KDM4EMMP2THRB | |
| Phosphoric Acid SCHEMBL8364791 | 0.91 | CA2 (0.36) | CA2SLC34A1KDM4EMMP2THRB | |
| Phosphoric Acid SCHEMBL19556281 | 0.91 | — | — | |
| Phosphoric Acid SCHEMBL5858383 | 0.87 | CA2 (0.33) | CA2SLC34A1 | |
| Phosphoric Acid SCHEMBL4870365 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2852568-B1 | PROCESS FOR MAKING DIMETHYL CARBONATE | COUNCIL SCIENT IND RES (IN) | 2016-08-17 | — | — | EP | disclosed |
| US-9073849-B2 | Process for making dimethyl carbonate | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-07-07 | — | — | US | disclosed |
| US-20150141690-A1 | PROCESS FOR MAKING DIMETHYL CARBONATE | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-05-21 | — | — | US | disclosed |
| EP-2852568-A1 | PROCESS FOR MAKING DIMETHYL CARBONATE | Council of Scientific & Industrial Research (IN) | 2015-04-01 | — | — | EP | disclosed |
| WO-2013175510-A1 | PROCESS FOR MAKING DIMETHYL CARBONATE | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-11-28 | — | — | WO | disclosed |
| US-5976486-A | FROM A SOURCE OF HYDROGEN AND OXYGEN IN THE PRESENCE OF A DISPERSION OF A CATALYST WHICH COMPRIZES PARTICLES COATED WITH 3-10 LAYERS OF A ZIRCONIUM OR HAFNIUM PHOSPHONATE COMPLEX | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 1999-11-02 | — | — | US | disclosed |
| WO-1999049971-A1 | METHOD FOR CATALYTIC PRODUCTION OF HYDROGEN PEROXIDE AND CATALYST THEREFOR | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 1999-10-07 | — | — | WO | disclosed |