Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 19/20 | 0.54 |
| ▸ | TACR2 | P21452 | 2/20 | 0.49 |
| ▸ | TACR3 | P29371 | 2/20 | 0.49 |
| ▸ | CCR5 | P51681 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8485199 | 0.85 | TACR1 (0.44) | TACR1TACR2TACR3 | |
| SCHEMBL8366723 | 0.83 | TACR1 (0.49) | TACR1TACR2TACR3 | |
| SCHEMBL8203185 | 0.80 | TACR1 (0.68) | TACR1TACR2TACR3CCR5 | |
| SCHEMBL4630131 | 0.77 | HSD11B1 (0.36) | TACR1TACR2TACR3 | |
| Hydrochloric Acid SCHEMBL8366693 | 0.77 | TACR1 (0.59) | TACR1TACR2TACR3 | |
| Hydrochloric Acid SCHEMBL8364665 | 0.76 | TACR1 (0.56) | TACR1TACR2TACR3CCR5 | |
| SCHEMBL8483549 | 0.75 | TACR1 (0.56) | TACR1TACR2TACR3 | |
| SCHEMBL8347511 | 0.74 | KDM4E (0.45) | TACR1TACR2TACR3CCR5 | |
| SCHEMBL7956540 | 0.74 | CCR5 (0.58) | TACR1TACR2TACR3CCR5 | |
| SCHEMBL8991919 | 0.74 | TACR1 (0.42) | TACR1TACR2TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965580-A | TREATMENT OF SUBSTANCE P- AND NEUROKININ-DEPENDENT DISORDERS | SANOFI (FR) | 1999-10-12 | — | — | US | disclosed |