SCHEMBL8364929

SCHEMBL8364929

CCN(CC)c1ccccc1Cc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.48
TSHR P16473 1/20 0.47
DRD2 P14416 2/20 0.46
DRD1 P21728 2/20 0.46
DRD3 P35462 1/20 0.46
PTPN1 P18031 2/20 0.45
CNR2 P34972 1/20 0.43
HTR2A P28223 1/20 0.42
CALM1 P0DP23 1/20 0.42
DRD4 P21917 1/20 0.41
DRD5 P21918 1/20 0.41
BCL2 P10415 1/20 0.41
BCL2L1 Q07817 1/20 0.41
HRH1 P35367 2/20 0.40
TP53 P04637 1/20 0.39
CYP1A2 P05177 1/20 0.38
LTA4H P09960 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1241839 0.87 AR (0.53) ARTSHRDRD2DRD1DRD3
Bromide SCHEMBL10963850 0.83 DRD2 (0.46) TSHRDRD2DRD1DRD3PTPN1
SCHEMBL5793551 0.82 HRH1 (0.43) DRD2DRD1DRD3PTPN1CNR2
SCHEMBL1704796 0.82 PTPN1 (0.45) ARTSHRPTPN1HTR2ACALM1
SCHEMBL29878136 0.79 PTPN1 (0.47) ARTSHRDRD2DRD1DRD3
SCHEMBL3165408 0.79 PTPN1 (0.47) ARTSHRDRD2DRD1DRD3
SCHEMBL462452 0.79 AR (0.49) ARTSHRCNR2L3MBTL1
SCHEMBL10659836 0.79 BCL2 (0.52) DRD2DRD1DRD3PTPN1HTR2A
SCHEMBL5852076 0.78 BCL2 (0.47) TSHRDRD2DRD1DRD3PTPN1
Water SCHEMBL11327197 0.78 PTPN1 (0.46) ARTSHRDRD2DRD1DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110922566-B Polyisocyanate composition, method for producing same, coating composition, and coating film 旭化成株式会社 2021-11-19 CN disclosed
CN-110922566-A Polyisocyanate composition, method for producing same, coating composition, and coating film 旭化成株式会社 2020-03-27 CN disclosed
US-5856013-A CHARGE TRANSPORT LAYER AND A FLUORINATED CARBON FILLED FLUOROELASTOMER LAYER. XEROX CORPORATION 1999-01-05 US disclosed
EP-0239353-B1 FABRICATION OF SEAMLESS SUBSTRATES XEROX CORPORATION (US) 1993-06-23 EP disclosed
EP-0145400-B1 PHOTOCONDUCTIVE DEVICES CONTAINING NOVEL SQUARAINE COMPOUNDS XEROX CORPORATION (US) 1991-05-29 EP disclosed
EP-0396828-A1 Unsymmetrical squaraine compositions and photoconductive imaging members using such compositions XEROX CORPORATION (US) 1990-11-14 EP disclosed
EP-0146301-B1 PROCESS FOR SYNTHESIZING SQUARAINE COMPOSITIONS XEROX CORPORATION (US) 1988-07-13 EP disclosed
US-4711833-A Powder coating process for seamless substrates XEROX CORPORATION (US) 1987-12-08 US disclosed
EP-0239353-A2 Fabrication of seamless substrates XEROX CORPORATION (US) 1987-09-30 EP disclosed
EP-0102850-B1 LAYERED PHOTORESPONSIVE DEVICE XEROX CORPORATION (US) 1987-05-20 EP disclosed
EP-0146301-A1 Process for synthesizing squaraine compositions XEROX CORPORATION (US) 1985-06-26 EP disclosed
EP-0144195-A2 Squaraine compositions XEROX CORPORATION (US) 1985-06-12 EP disclosed
US-4521621-A Novel squarine systems XEROX CORPORATION (US) 1985-06-04 US disclosed
US-4486520-A Photoconductive devices containing novel squaraine compositions XEROX CORPORATION (US) 1984-12-04 US disclosed
US-4471041-A Photoconductive devices containing novel squaraine compositions XEROX CORPORATION (US) 1984-09-11 US disclosed
US-4467023-A Layered photoresponsive device containing hole injecting ground electrode XEROX CORPORATION (US) 1984-08-21 US disclosed
EP-0102850-A1 Layered photoresponsive device XEROX CORPORATION (US) 1984-03-14 EP disclosed
US-4275132-A ELECTROGRAPHIC CARBON BLACK OR GRAPHITE DISPERSED IN A POLYMER SPECIFICALLY A POLYESTER XEROX CORPORATION (US) 1981-06-23 US disclosed
US-4251612-A CARBON OR GRAPHITE DISPERSED IN POLYMER, HOLE INJECTING MATERIAL, HOLE TRANSPORT LAYER XEROX CORPORATION (US) 1981-02-17 US disclosed