Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30510249 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL8193181 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL8193173 | 0.94 | — | — | |
| SCHEMBL30740431 | 0.94 | — | — | |
| SCHEMBL149603 | 0.94 | ALDH1A1 (0.30) | — | |
| SCHEMBL30740392 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL8368817 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL15153246 | 0.88 | KDM4E (0.31) | KDM4EPMP22ATM | |
| Hydrochloric Acid SCHEMBL6280773 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL8367826 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889060-A1 | Transition metal-magnesium catalyst precursors, catalysts and polymerization processes | Chevron Chemical Company LLC (US) | 1999-01-07 | — | — | EP | disclosed |