Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.35 |
| ▸ | FNTA | P49354 | 2/20 | 0.35 |
| ▸ | FNTB | P49356 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 4/20 | 0.33 |
| ▸ | PPARD | Q03181 | 4/20 | 0.33 |
| ▸ | PPARA | Q07869 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1286855 | 0.81 | EP300 (0.38) | EP300FNTAFNTBCES2THRB | |
| SCHEMBL1286854 | 0.81 | EP300 (0.38) | EP300FNTAFNTBCES2THRB | |
| SCHEMBL2878896 | 0.80 | PTGS1 (0.35) | — | |
| SCHEMBL5856231 | 0.79 | EP300 (0.37) | EP300FNTAFNTBCES2THRB | |
| SCHEMBL11057592 | 0.79 | PTGS1 (0.32) | — | |
| SCHEMBL15577114 | 0.78 | CES2 (0.43) | EP300FNTAFNTBCES2THRB | |
| SCHEMBL15791978 | 0.78 | EP300 (0.40) | EP300FNTAFNTBCES2THRB | |
| SCHEMBL15791892 | 0.78 | EP300 (0.40) | EP300FNTAFNTBCES2THRB | |
| SCHEMBL9418790 | 0.76 | CES2 (0.46) | EP300FNTAFNTBCES2THRB | |
| SCHEMBL561739 | 0.76 | CES2 (0.46) | EP300FNTAFNTBCES2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648811-B1 | Thermoplastic resin compositions with high impact strength at low temperature | CHEIL IND INC (KR) | 1999-01-13 | — | — | EP | claimed |
| EP-0648811-A2 | Thermoplastic resin compositions with high impact strength at low temperature | CHEIL INDUSTRIES INC. (KR) | 1995-04-19 | — | — | EP | claimed |
| EP-0648811-B1 | Thermoplastic resin compositions with high impact strength at low temperature | CHEIL IND INC (KR) | 1999-01-13 | — | — | EP | disclosed |
| EP-0648811-A2 | Thermoplastic resin compositions with high impact strength at low temperature | CHEIL INDUSTRIES INC. (KR) | 1995-04-19 | — | — | EP | disclosed |