SCHEMBL8366245

SCHEMBL8366245

C=C(CCCCCCC(Cl)Cl)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 2/20 0.40
TET2 Q6N021 3/20 0.34
TET3 O43151 1/20 0.34
TET1 Q8NFU7 1/20 0.34
GSTK1 Q9Y2Q3 2/20 0.34
GRIK1 P39086 1/20 0.33
GRIK2 Q13002 1/20 0.33
GRM1 Q13255 1/20 0.33
GRM2 Q14416 1/20 0.33
LMNA P02545 1/20 0.33
TSHR P16473 1/20 0.33
NFKB1 P19838 1/20 0.33
PMP22 Q01453 1/20 0.33
FFAR4 Q5NUL3 1/20 0.33
FFAR1 O14842 1/20 0.33
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5544540 0.82 TET2 (0.39) TBXAS1TET2TET3TET1GRIK1
SCHEMBL11120675 0.82 TBXAS1 (0.50) TBXAS1TET2TET3TET1GRIK1
SCHEMBL1865932 0.82 TBXAS1 (0.50) TBXAS1TET2TET3TET1GRIK1
SCHEMBL11123265 0.82 TBXAS1 (0.50) TBXAS1TET2TET3TET1GRIK1
SCHEMBL1860769 0.82 TBXAS1 (0.50) TBXAS1TET2TET3TET1GRIK1
SCHEMBL11122641 0.82 TBXAS1 (0.50) TBXAS1TET2TET3TET1GRIK1
SCHEMBL3125930 0.82 TBXAS1 (0.50) TBXAS1TET2TET3TET1GRIK1
SCHEMBL1863088 0.82 TBXAS1 (0.50) TBXAS1TET2TET3TET1GRIK1
SCHEMBL11125055 0.82 TBXAS1 (0.50) TBXAS1TET2TET3TET1GRIK1
SCHEMBL1249194 0.82 TBXAS1 (0.50) TBXAS1TET2TET3TET1GRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648811-B1 Thermoplastic resin compositions with high impact strength at low temperature CHEIL IND INC (KR) 1999-01-13 EP claimed
EP-0648811-A2 Thermoplastic resin compositions with high impact strength at low temperature CHEIL INDUSTRIES INC. (KR) 1995-04-19 EP claimed
EP-0648811-B1 Thermoplastic resin compositions with high impact strength at low temperature CHEIL IND INC (KR) 1999-01-13 EP disclosed
EP-0648811-A2 Thermoplastic resin compositions with high impact strength at low temperature CHEIL INDUSTRIES INC. (KR) 1995-04-19 EP disclosed