⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258011 | 0.72 | — | — | |
| SCHEMBL9285114 | 0.72 | — | — | |
| SCHEMBL4617564 | 0.70 | — | — | |
| SCHEMBL17236310 | 0.70 | — | — | |
| SCHEMBL363396 | 0.70 | — | — | |
| SCHEMBL9482405 | 0.67 | — | — | |
| SCHEMBL4384894 | 0.66 | KDM4E (0.36) | — | |
| SCHEMBL9812598 | 0.65 | — | — | |
| SCHEMBL2225565 | 0.65 | CDC25A (0.35) | — | |
| SCHEMBL9767231 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2867205-B1 | NOVEL CHOLECYSTOKININ RECEPTOR LIGANDS | PNB VESPER LIFE SCIENCE PVT LTD (IN) | 2018-12-19 | — | — | EP | disclosed |
| CN-106478517-A | A kind of synthetic method of 2 methyl 5 chlorine 2H-Pyridazin-3-one | 安徽省鸿鑫生物科技有限公司 | 2017-03-08 | — | — | CN | disclosed |
| EP-2867205-A1 | NOVEL CHOLECYSTOKININ RECEPTOR LIGANDS | PNB Vesper Life Science Pvt Limited (IN) | 2015-05-06 | — | — | EP | disclosed |
| US-8921577-B2 | Cholecystokinin receptor ligands | PNB Vesper Life Sciences Pvt. Ltd. (IN) | 2014-12-30 | — | — | US | disclosed |
| WO-2014006629-A1 | NOVEL CHOLECYSTOKININ RECEPTOR LIGANDS | PNB VESPER LIFE SCIENCE PVT LIMITED (IN) | 2014-01-09 | — | — | WO | disclosed |
| US-20140005248-A1 | NOVEL CHOLECYSTOKININ RECEPTOR LIGANDS | PNB VESPER LIFE SCIENCES PVT LTD. (IN) | 2014-01-02 | — | — | US | disclosed |
| US-8143253-B2 | Organic compounds | NOVARTIS AG (CH) | 2012-03-27 | — | — | US | disclosed |
| US-8143253-B2 | Organic compounds | NOVARTIS AG (CH) | 2012-03-27 | — | — | US | disclosed |
| US-8143253-B2 | Organic compounds | NOVARTIS AG (CH) | 2012-03-27 | — | — | US | disclosed |
| EP-2183027-B1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2011-08-31 | — | — | EP | disclosed |
| EP-2183027-B1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2011-08-31 | — | — | EP | disclosed |
| US-20100204235-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2010-08-12 | — | — | US | disclosed |
| US-20100204235-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2010-08-12 | — | — | US | disclosed |
| US-20100204235-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2010-08-12 | — | — | US | disclosed |
| EP-2183027-A1 | ORGANIC COMPOUNDS | Novartis Ag (CH) | 2010-05-12 | — | — | EP | disclosed |
| WO-2009013335-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2009-01-29 | — | — | WO | disclosed |
| WO-2009013335-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2009-01-29 | — | — | WO | disclosed |
| US-20070123718-A1 | Novel 4-amino-2(5H)-furanones | ASTON UNIVERSITY (GB) | 2007-05-31 | — | — | US | disclosed |
| EP-1628966-A2 | 4-AMINO-2(5H)-FURANONES USEFUL AS CHOLECYSTOKININ ANTAGONISTS | Aston University (GB) | 2006-03-01 | — | — | EP | disclosed |
| WO-2004106315-A2 | 4-AMINO-2(5H)-FURANONES USEFUL AS CHOLECYSTOKININ ANTAGONISTS | ASTON UNIVERSITY (GB) | 2004-12-09 | — | — | WO | disclosed |