Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 10/20 | 0.35 |
| ▸ | CDC25B | P30305 | 9/20 | 0.35 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7296014 | 0.70 | PDCD4 (0.47) | CDC25ACDC25B | |
| SCHEMBL363396 | 0.70 | — | — | |
| SCHEMBL2279671 | 0.69 | PTGS2 (0.35) | CDC25ACDC25B | |
| SCHEMBL9422969 | 0.68 | PDCD4 (0.42) | CDC25ACDC25B | |
| SCHEMBL9258011 | 0.67 | — | — | |
| SCHEMBL9285114 | 0.67 | — | — | |
| SCHEMBL9266271 | 0.66 | CA1 (0.48) | ALDH1A1 | |
| SCHEMBL9038940 | 0.65 | NFE2L2 (0.39) | — | |
| SCHEMBL836656 | 0.65 | — | — | |
| SCHEMBL4617564 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701667-B2 | Coumarin-based fluorogenic agents and uses thereof for specific protein labelling | UNIVERSITY OF OTTAWA (CA) | 2017-07-11 | — | — | US | disclosed |
| US-9701667-B2 | Coumarin-based fluorogenic agents and uses thereof for specific protein labelling | UNIVERSITY OF OTTAWA (CA) | 2017-07-11 | — | — | US | disclosed |
| US-9701667-B2 | Coumarin-based fluorogenic agents and uses thereof for specific protein labelling | UNIVERSITY OF OTTAWA (CA) | 2017-07-11 | — | — | US | disclosed |
| US-20150316557-A1 | COUMARIN-BASED FLUOROGENIC AGENTS AND USES THEREOF FOR SPECIFIC PROTEIN LABELLING | UNIVERSITY OF OTTAWA (CA) | 2015-11-05 | — | — | US | disclosed |
| US-20150316557-A1 | COUMARIN-BASED FLUOROGENIC AGENTS AND USES THEREOF FOR SPECIFIC PROTEIN LABELLING | UNIVERSITY OF OTTAWA (CA) | 2015-11-05 | — | — | US | disclosed |
| US-20150316557-A1 | COUMARIN-BASED FLUOROGENIC AGENTS AND USES THEREOF FOR SPECIFIC PROTEIN LABELLING | UNIVERSITY OF OTTAWA (CA) | 2015-11-05 | — | — | US | disclosed |
| WO-2011086566-A1 | METHOD OF RESOLUTION OF (RS) - 1, 1 ' - BI - 2 - NAPHTHOL FOR OBTAINING ENANTIOMERIC PURE I.E. (S) - (-) \" 1, 1 ' \"BI - 2 -NAPHTHOL AND/OR (R) - ( ) - 1, 1 ' - BI - 2 - NAPHTHOL VIA CO - CRYSTAL FORMATION WITH OPTICALLY ACTIVE DERIVATIVES OF GAMMA -AMINO ACIDS | LUPIN LIMITED (IN) | 2011-07-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150316557-A1 | COUMARIN-BASED FLUOROGENIC AGENTS AND USES THEREOF FOR SPECIFIC PROTEIN LABELLING | PFDN1, PFDN6, CDC73 | CDC25A 2648/4885CDC25B 2677/4885RPS6KA5 1742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.