Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.48 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.48 |
| ▸ | MCTS1 | Q9ULC4 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8364781 | 0.89 | MARS1 (0.53) | MARS1NPC1SLC16A3SLC16A1MCTS1 | |
| SCHEMBL8367181 | 0.89 | MARS1 (0.65) | MARS1NPC1SLC16A3SLC16A1MCTS1 | |
| Hydrochloric Acid SCHEMBL8364783 | 0.88 | MARS1 (0.64) | MARS1NPC1SLC16A3SLC16A1MCTS1 | |
| SCHEMBL8364840 | 0.84 | NPC1 (0.51) | MARS1NPC1SLC16A3SLC16A1MCTS1 | |
| SCHEMBL3198943 | 0.76 | SMN1; SMN2 (0.72) | MARS1NPC1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL8364640 | 0.75 | CNR2 (0.51) | NPC1SLC16A3SLC16A1MCTS1SMN1; SMN2 | |
| SCHEMBL4852086 | 0.73 | NPC1 (0.49) | MARS1NPC1SLC16A3SLC16A1MCTS1 | |
| SCHEMBL3103714 | 0.73 | MAPT (0.51) | NPC1SMN1; SMN2LMNAALDH1A1TP53 | |
| SCHEMBL3215777 | 0.71 | PPARG (0.65) | MARS1NPC1SLC16A3SLC16A1MCTS1 | |
| SCHEMBL17727586 | 0.71 | NPC1 (0.69) | MARS1NPC1SMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925768-A | ANTIINFLAMMATORY AGENTS; ANALGESICS, ANTICOAGULANTS, NARCOTICS | SANOFI (FR) | 1999-07-20 | — | — | US | disclosed |