Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.45 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RPA1 | P27694 | 3/20 | 0.43 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.43 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8364849 | 0.91 | RPA1 (0.53) | SMN1; SMN2ALDH1A1CYP1A2CYP2C19SMPD1 | |
| SCHEMBL8369821 | 0.91 | HDAC3 (0.49) | SMN1; SMN2ALDH1A1CYP1A2CYP2C19MALT1 | |
| SCHEMBL8369156 | 0.90 | NPBWR1 (0.46) | SMN1; SMN2ALDH1A1CYP1A2CYP2C19SMPD1 | |
| SCHEMBL8369155 | 0.90 | RPA1 (0.54) | ALDH1A1SMPD1NPBWR1MALT1RPA1 | |
| SCHEMBL8369823 | 0.89 | NPBWR1 (0.45) | SMN1; SMN2ALDH1A1CYP1A2CYP2C19SMPD1 | |
| Hydrochloric Acid SCHEMBL8369158 | 0.89 | RPA1 (0.53) | ALDH1A1SMPD1NPBWR1MALT1RPA1 | |
| SCHEMBL8367190 | 0.89 | MEN1 (0.53) | SMN1; SMN2ALDH1A1CYP1A2CYP2C19SMPD1 | |
| SCHEMBL8366684 | 0.89 | MEN1 (0.53) | SMN1; SMN2ALDH1A1CYP1A2CYP2C19NPBWR1 | |
| SCHEMBL8366421 | 0.88 | NOTUM (0.46) | SMN1; SMN2ALDH1A1CYP1A2CYP2C19MALT1 | |
| SCHEMBL8369228 | 0.88 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1CYP1A2CYP2C19SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925768-A | ANTIINFLAMMATORY AGENTS; ANALGESICS, ANTICOAGULANTS, NARCOTICS | SANOFI (FR) | 1999-07-20 | — | — | US | disclosed |