Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 4/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8369821 | 0.91 | HDAC3 (0.49) | MEN1KMT2AHDAC6HDAC3HDAC4 | |
| SCHEMBL8366716 | 0.89 | SMN1; SMN2 (0.53) | MEN1KMT2AMALT1POLBSMPD1 | |
| SCHEMBL8366684 | 0.89 | MEN1 (0.53) | MEN1KMT2AHDAC6HDAC3HDAC4 | |
| SCHEMBL8366421 | 0.88 | NOTUM (0.46) | MEN1KMT2AMALT1POLBTP53 | |
| SCHEMBL8364650 | 0.88 | MARS1 (0.54) | MEN1KMT2AHDAC6HDAC3HDAC4 | |
| SCHEMBL8366951 | 0.88 | MEN1 (0.53) | MEN1KMT2AHDAC6HDAC3HDAC4 | |
| SCHEMBL8366411 | 0.85 | MEN1 (0.49) | MEN1KMT2AMALT1POLB | |
| SCHEMBL8368094 | 0.84 | HDAC3 (0.50) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8368121 | 0.83 | HDAC3 (0.47) | MEN1KMT2AHDAC6HDAC3HDAC4 | |
| SCHEMBL27486656 | 0.81 | HDAC6 (0.48) | HDAC6HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925768-A | ANTIINFLAMMATORY AGENTS; ANALGESICS, ANTICOAGULANTS, NARCOTICS | SANOFI (FR) | 1999-07-20 | — | — | US | disclosed |