Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 10/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6543222 | 0.73 | SLC6A4 (0.46) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7811639 | 0.69 | SLC6A4 (0.61) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL6543319 | 0.69 | SLC6A4 (0.45) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL8367017 | 0.69 | SLC6A3 (0.42) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL8564503 | 0.69 | SLC6A3 (0.37) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL6992040 | 0.67 | SLC6A4 (0.47) | SLC6A4SLC6A3SLC6A2OPRM1BACE1 | |
| SCHEMBL7810280 | 0.67 | SLC6A4 (0.47) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7811794 | 0.66 | SLC6A4 (0.44) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL5901153 | 0.66 | SLC6A4 (0.43) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL27528569 | 0.66 | SLC6A4 (0.43) | SLC6A4SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5942523-A | NOVEL PIPERIDINE DERIVATIVES WHOSE SPECIFIC STRUCTURE INCLUDES AT POSITION 1 AN ALKYL CHAIN HAVING A 3,4-DICHLOROPHENYL GROUP ATTACHED; HIGH SELECTIVITY TO THE NK3 RECEPTOR; UNIT DOSAGE FORM; TREATING PSYCHIATRIC DISEASES | SANOFI (FR) | 1999-08-24 | — | — | US | disclosed |
| US-5741910-A | PIPERIDINE DERIVATIVE INTERMEDIATES | SANOFI (FR) | 1998-04-21 | — | — | US | disclosed |