Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MALT1 | Q9UDY8 | 4/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.49 |
| ▸ | CNR2 | P34972 | 4/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8368039 | 0.90 | NPC1 (0.51) | NPC1RAB9AMALT1CNR2CNR1 | |
| SCHEMBL8046115 | 0.83 | RPA1 (0.63) | MALT1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8369218 | 0.83 | RPA1 (0.51) | MALT1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8368094 | 0.83 | HDAC3 (0.50) | RAB9AMALT1HDAC3HDAC4HDAC1 | |
| SCHEMBL8366452 | 0.82 | RPA1 (0.50) | MALT1HDAC3HDAC4HDAC1HDAC7 | |
| Hydrochloric Acid SCHEMBL8369220 | 0.82 | RPA1 (0.62) | MALT1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8369101 | 0.78 | RPA1 (0.61) | MALT1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8366637 | 0.77 | HDAC3 (0.42) | MALT1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8369875 | 0.76 | MARS1 (0.56) | MALT1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8369821 | 0.75 | HDAC3 (0.49) | RAB9AMALT1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925768-A | ANTIINFLAMMATORY AGENTS; ANALGESICS, ANTICOAGULANTS, NARCOTICS | SANOFI (FR) | 1999-07-20 | — | — | US | disclosed |