Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8367198 | 1.00 | MAPT (0.69) | MAPTALDH1A1KDM4ECES2CES1 | |
| SCHEMBL27101307 | 0.88 | KDM4E (0.65) | MAPTALDH1A1KDM4EGAALMNA | |
| SCHEMBL8369833 | 0.86 | ALDH1A1 (0.63) | MAPTALDH1A1KDM4ETAS1R3TAS1R1 | |
| SCHEMBL8369834 | 0.86 | ALDH1A1 (0.63) | MAPTALDH1A1KDM4ETAS1R3TAS1R1 | |
| SCHEMBL8040827 | 0.83 | CA12 (0.55) | MAPTALDH1A1KDM4ECES2CES1 | |
| SCHEMBL8040833 | 0.83 | CA12 (0.55) | MAPTALDH1A1KDM4ECES2CES1 | |
| SCHEMBL8368078 | 0.81 | ALDH1A1 (1.00) | MAPTALDH1A1KDM4ECES2CES1 | |
| SCHEMBL8368077 | 0.81 | ALDH1A1 (1.00) | MAPTALDH1A1KDM4ECES2CES1 | |
| SCHEMBL3681348 | 0.79 | KDM4E (0.62) | MAPTALDH1A1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL8367177 | 0.79 | KDM4E (0.62) | MAPTALDH1A1KDM4ESMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925768-A | ANTIINFLAMMATORY AGENTS; ANALGESICS, ANTICOAGULANTS, NARCOTICS | SANOFI (FR) | 1999-07-20 | — | — | US | disclosed |