Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7663691 | 0.89 | ASH1L (0.38) | RAB9ALMNAMEN1KMT2ATDP1 | |
| SCHEMBL8516843 | 0.88 | CAMK2D (0.49) | CAMK2DGSK3B | |
| SCHEMBL8366761 | 0.87 | ASH1L (0.37) | RAB9ALMNAMEN1KMT2ATDP1 | |
| SCHEMBL8516619 | 0.87 | ASH1L (0.43) | RAB9ALMNAMEN1KMT2ATDP1 | |
| SCHEMBL8366774 | 0.87 | ASH1L (0.34) | RAB9ALMNAMEN1KMT2ATDP1 | |
| SCHEMBL8516327 | 0.86 | CAMK2D (0.46) | CAMK2DGSK3B | |
| SCHEMBL8368545 | 0.85 | CAMK2D (0.38) | CAMK2D | |
| SCHEMBL7659523 | 0.84 | ASH1L (0.35) | LMNAMEN1KMT2ATDP1MAPT | |
| SCHEMBL7654550 | 0.84 | KMT2A (0.36) | LMNAMEN1KMT2ATDP1MAPT | |
| SCHEMBL8365260 | 0.84 | CAMK2D (0.41) | RAB9AMEN1KMT2AMAPTCAMK2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | claimed |
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | disclosed |