Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.43 |
| ▸ | CAMK2D | Q13557 | 7/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | QPCT | Q16769 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CFTR | P13569 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8516793 | 0.88 | CAMK2D (0.48) | CAMK2DGSK3B | |
| SCHEMBL8367882 | 0.87 | RAB9A (0.44) | ASH1LCAMK2DGSK3BQPCTTDP1 | |
| SCHEMBL8516977 | 0.86 | CAMK2D (0.46) | CAMK2D | |
| SCHEMBL7663691 | 0.85 | ASH1L (0.38) | ASH1LCAMK2DGSK3BQPCTTDP1 | |
| SCHEMBL8515918 | 0.85 | IGF1R (0.39) | CAMK2DMAPT | |
| SCHEMBL8516997 | 0.84 | ASH1L (0.37) | ASH1LCAMK2DGSK3BQPCTTDP1 | |
| SCHEMBL8516993 | 0.84 | CAMK2D (0.37) | CAMK2DGSK3BTDP1MAPT | |
| SCHEMBL8516344 | 0.83 | CAMK2D (0.40) | CAMK2DGSK3BQPCTPDE4BPDE4D | |
| SCHEMBL8515897 | 0.83 | CAMK2D (0.44) | CAMK2DGSK3BQPCT | |
| SCHEMBL8366761 | 0.82 | ASH1L (0.37) | ASH1LTDP1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | claimed |
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | disclosed |