Ether

Ether

SCHEMBL8368264

CCOCC.O=S(=O)(O)c1ccccc1-c1ccccc1

nearest known ligand 0.40

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Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 2/20 0.40
PTGS2 P35354 1/20 0.40
LMNA P02545 1/20 0.38
AKR1B1 P15121 1/20 0.37
EDNRA P25101 5/20 0.37
EDNRB P24530 4/20 0.37
ALDH1A1 P00352 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MYC P01106 1/20 0.37
PTPN1 P18031 1/20 0.36
SCN1A P35498 1/20 0.35
SCN2A Q99250 1/20 0.35
SCN3A Q9NY46 1/20 0.35
TSHR P16473 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL2731654 0.90 MYC (0.41) LMNAL3MBTL1MYCTSHRSMN1; SMN2
Ether SCHEMBL2731657 0.89 PTGS2 (0.37) CASP1PTGS2LMNAALDH1A1L3MBTL1
SCHEMBL29743050 0.86 CASP1 (0.47) CASP1PTGS2AKR1B1EDNRAEDNRB
SCHEMBL232659 0.86 CASP1 (0.47) CASP1PTGS2AKR1B1EDNRAEDNRB
Hydrochloric Acid SCHEMBL11757790 0.84 CASP1 (0.46) CASP1PTGS2AKR1B1EDNRAEDNRB
SCHEMBL29194067 0.84 CASP1 (0.46) CASP1PTGS2AKR1B1EDNRAEDNRB
Water SCHEMBL27371066 0.84 CASP1 (0.46) CASP1PTGS2AKR1B1EDNRAEDNRB
Lithium SCHEMBL3173875 0.84 CASP1 (0.46) CASP1PTGS2AKR1B1EDNRAEDNRB
SCHEMBL28934633 0.84 CASP1 (0.46) CASP1PTGS2AKR1B1EDNRAEDNRB
SCHEMBL1870052 0.84 CASP1 (0.46) CASP1PTGS2AKR1B1EDNRAEDNRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5973195-A Surfactants derived from 2-(2-hydroxyphenyl)benzenesulfinate and alkyl-substituted derivatives ENERGY BIOSYSTEMS CORPORATION (US) 1999-10-26 US disclosed
WO-1999047496-A1 SURFACTANTS DERIVED FROM 2-(2-HYDROXYPHENYL) BENZENESULFINATE ENERGY BIOSYSTEMS CORPORATION (US) 1999-09-23 WO disclosed