Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8368301 | 1.00 | HIF1A (0.49) | HIF1AMAPK1KMT2ATSHRL3MBTL1 | |
| SCHEMBL9018933 | 0.88 | HIF1A (0.51) | HIF1AL3MBTL1TDP1NPC1RAB9A | |
| SCHEMBL8369636 | 0.88 | HIF1A (0.51) | HIF1AL3MBTL1TDP1NPC1RAB9A | |
| SCHEMBL8369635 | 0.88 | HIF1A (0.51) | HIF1AL3MBTL1TDP1NPC1RAB9A | |
| SCHEMBL8780118 | 0.86 | HIF1A (0.51) | HIF1A | |
| SCHEMBL8370696 | 0.86 | HIF1A (0.51) | HIF1A | |
| SCHEMBL8370701 | 0.86 | HIF1A (0.51) | HIF1A | |
| SCHEMBL6894980 | 0.86 | HIF1A (0.48) | HIF1AKMT2ATDP1NPC1RAB9A | |
| SCHEMBL8372363 | 0.84 | HIF1A (0.48) | HIF1AKMT2AL3MBTL1HPGDKDM4E | |
| SCHEMBL7566354 | 0.84 | HIF1A (0.48) | HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0617011-B1 | Process for producing alkoxyiminoacetamide compounds | SHIONOGI & CO (JP) | 1999-01-20 | — | — | EP | disclosed |
| US-5506358-A | USEFUL AS AGRICULTURAL FUNGICIDES | SHIONOGI & CO., LTD. (JP) | 1996-04-09 | — | — | US | disclosed |
| EP-0617011-A2 | Process for producing alkoxyiminoacetamide compounds | SHIONOGI & CO., LTD. (JP) | 1994-09-28 | — | — | EP | disclosed |