Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8369635 | 1.00 | HIF1A (0.51) | HIF1AL3MBTL1TDP1NPC1RAB9A | |
| SCHEMBL8369636 | 1.00 | HIF1A (0.51) | HIF1AL3MBTL1TDP1NPC1RAB9A | |
| SCHEMBL8368301 | 0.88 | HIF1A (0.49) | HIF1AL3MBTL1TDP1NPC1RAB9A | |
| SCHEMBL8368303 | 0.88 | HIF1A (0.49) | HIF1AL3MBTL1TDP1NPC1RAB9A | |
| SCHEMBL8369852 | 0.85 | HIF1A (0.63) | HIF1AL3MBTL1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL8399406 | 0.85 | HIF1A (0.63) | HIF1AL3MBTL1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL8369854 | 0.85 | HIF1A (0.63) | HIF1AL3MBTL1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL8372760 | 0.84 | HIF1A (0.46) | HIF1ASGMS2TP53HTTCASP3 | |
| SCHEMBL8368480 | 0.84 | HIF1A (0.46) | HIF1ASGMS2TP53HTTCASP3 | |
| SCHEMBL8368481 | 0.84 | HIF1A (0.46) | HIF1ASGMS2TP53HTTCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0629609-B1 | Process for the preparation of Alkoxyiminoacetamide derivatives and an intermediate therefor | SHIONOGI & CO (JP) | 1996-12-04 | — | — | EP | disclosed |
| EP-0398692-B1 | Alkoxyiminoacetamide derivatives and their use as fungicides | SHIONOGI & CO (JP) | 1996-08-21 | — | — | EP | disclosed |
| EP-0629609-A1 | Process for the preparation of Alkoxyiminoacetamide derivatives and an intermediate therefor | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1994-12-21 | — | — | EP | disclosed |