Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 7/20 | 0.41 |
| ▸ | RAB9A | P51151 | 7/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8368303 | 0.86 | HIF1A (0.49) | HIF1ATDP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8368301 | 0.86 | HIF1A (0.49) | HIF1ATDP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8205297 | 0.79 | HIF1A (0.50) | HIF1ATDP1KMT2ATP53 | |
| SCHEMBL7779845 | 0.79 | HIF1A (0.50) | HIF1ATDP1KMT2ATP53 | |
| SCHEMBL8103837 | 0.78 | HIF1A (0.47) | HIF1A | |
| SCHEMBL8103618 | 0.78 | HIF1A (0.47) | HIF1A | |
| SCHEMBL8103619 | 0.78 | HIF1A (0.47) | HIF1A | |
| SCHEMBL7539620 | 0.78 | HIF1A (0.62) | HIF1ANPC1RAB9A | |
| SCHEMBL10433828 | 0.77 | HIF1A (0.45) | HIF1ATDP1NPC1RAB9APKM | |
| SCHEMBL8078567 | 0.77 | HIF1A (0.45) | HIF1ATDP1NPC1RAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040002545-A1 | Thiazole derivatives of 2-methoxyimino-2-(pyridinyloxymethyl)-phenyl-acetamides useful as fungicides | CETUSIC JEANNIE RACHEL (US) | 2004-01-01 | — | — | US | disclosed |
| CN-1461306-A | Thiazole derivatives of 2-methoxyimino-2- (pyridyloxymethyl) phenylacetamides as fungicides | DOW AGROSCIENCES LLC (US) | 2003-12-10 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040002545-A1 | Thiazole derivatives of 2-methoxyimino-2-(pyridinyloxymethyl)-phenyl-acetamides useful as fungicides | AADAC, NAT1, CNPY2 | HIF1A 4608/4885TDP1 3509/4885NPC1 4273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.