Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.84 |
| ▸ | DHODH | Q02127 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | RXRA | P19793 | 2/20 | 0.61 |
| ▸ | RXRB | P28702 | 2/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.57 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.57 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.53 |
| ▸ | FEN1 | P39748 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31752544 | 0.94 | KMO (0.95) | KMODHODHLMNAGAARXRA | |
| SCHEMBL30436085 | 0.94 | KMO (0.95) | KMODHODHLMNAGAARXRA | |
| SCHEMBL250880 | 0.94 | KMO (0.95) | KMODHODHLMNAGAARXRA | |
| Acetic Acid SCHEMBL29287805 | 0.92 | KMO (0.84) | KMODHODHLMNAGAARXRA | |
| SCHEMBL3220396 | 0.91 | KMO (0.91) | KMODHODHLMNAGAARXRA | |
| SCHEMBL28708895 | 0.91 | KMO (0.91) | KMODHODHLMNAGAARXRA | |
| Hydrochloric Acid SCHEMBL30713416 | 0.91 | KMO (0.91) | KMODHODHLMNAGAARXRA | |
| Biphenyl SCHEMBL9652651 | 0.91 | KMO (0.91) | KMODHODHLMNAGAARXRA | |
| SCHEMBL849169 | 0.91 | KMO (1.00) | KMODHODHLMNAGAARXRA | |
| SCHEMBL28690696 | 0.91 | KMO (0.91) | KMODHODHLMNAGAARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1257481-A | Pyridine derivatives and pharmaceutical compositions containing them | ASTRA PHARMA PROD (GB) | 2000-06-21 | — | — | CN | claimed |
| EP-0794789-A4 | INHIBITORS OF PRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 1999-05-26 | — | — | EP | claimed |
| EP-0794789-A1 | INHIBITORS OF PRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1997-09-17 | — | — | EP | claimed |