Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3767625 | 0.81 | QPCT (0.54) | SQORKMT2AMAPTCASP1KDM4E | |
| SCHEMBL24713444 | 0.71 | SQOR (0.53) | SQORKMT2AMAPTCASP1KDM4E | |
| SCHEMBL11741475 | 0.71 | NCOA1 (0.52) | SQORKMT2AMAPTCASP1ALDH1A1 | |
| SCHEMBL30439186 | 0.70 | MAPT (0.56) | SQORKMT2AMAPTCASP1ALDH1A1 | |
| SCHEMBL20764961 | 0.70 | MAPT (0.56) | SQORKMT2AMAPTCASP1ALDH1A1 | |
| SCHEMBL30505741 | 0.69 | SQOR (0.59) | SQORKMT2AMAPTCASP1KDM4E | |
| SCHEMBL29131667 | 0.69 | SQOR (0.59) | SQORKMT2AMAPTCASP1KDM4E | |
| SCHEMBL27852466 | 0.69 | SQOR (0.54) | SQORKMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL6916456 | 0.69 | ALOX5AP (0.51) | SQORKMT2AMAPTCASP1ALDH1A1 | |
| SCHEMBL5912697 | 0.68 | SQOR (0.45) | SQORKMT2AMAPTCASP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003033671-A2 | HUMAN GLUCAGON-LIKE-PEPTIDE-1 MIMICS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-04-24 | — | — | WO | disclosed |