Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | ITGAL | P20701 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | CRHBP | P24387 | 2/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8368483 | 1.00 | TRPA1 (0.37) | TRPA1ABCG2ITGB2ICAM1ITGAL | |
| SCHEMBL441277 | 0.84 | TRPA1 (0.42) | TRPA1ABCG2ITGB2ICAM1ITGAL | |
| SCHEMBL15704081 | 0.73 | TRPA1 (0.37) | TRPA1ABCG2ITGB2ICAM1ITGAL | |
| SCHEMBL15704079 | 0.73 | TRPA1 (0.37) | TRPA1ABCG2ITGB2ICAM1ITGAL | |
| SCHEMBL28450931 | 0.70 | TRPA1 (0.33) | TRPA1 | |
| SCHEMBL29281312 | 0.70 | TRPA1 (0.33) | TRPA1 | |
| SCHEMBL29501154 | 0.68 | ITGB2 (0.46) | TRPA1ABCG2ITGB2ICAM1ITGAL | |
| SCHEMBL30094684 | 0.68 | TRPA1 (0.39) | TRPA1ABCG2ITGB2ICAM1ITGAL | |
| SCHEMBL3757406 | 0.68 | ITGB2 (0.46) | TRPA1ABCG2ITGB2ICAM1ITGAL | |
| SCHEMBL30518914 | 0.68 | TRPA1 (0.33) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999046266-A1 | BENZOXADIAZOCINYL ARTHROPODICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-09-16 | — | — | WO | disclosed |