Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.39 |
| ▸ | ITGAL | P20701 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CRHBP | P24387 | 2/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | UBE2N | P61088 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29281312 | 0.84 | TRPA1 (0.33) | TRPA1 | |
| SCHEMBL28450931 | 0.84 | TRPA1 (0.33) | TRPA1ALOX5TSHRPKM | |
| SCHEMBL8368487 | 0.84 | TRPA1 (0.37) | TRPA1ABCG2ITGB2ICAM1ITGAL | |
| SCHEMBL8368483 | 0.84 | TRPA1 (0.37) | TRPA1ABCG2ITGB2ICAM1ITGAL | |
| SCHEMBL29501154 | 0.78 | ITGB2 (0.46) | TRPA1ABCG2ITGB2ICAM1ITGAL | |
| SCHEMBL3757406 | 0.78 | ITGB2 (0.46) | TRPA1ABCG2ITGB2ICAM1ITGAL | |
| SCHEMBL30094684 | 0.78 | TRPA1 (0.39) | TRPA1ABCG2ITGB2ICAM1ITGAL | |
| SCHEMBL8182698 | 0.75 | ITGB2 (0.43) | TRPA1ABCG2ITGB2ICAM1ITGAL | |
| SCHEMBL7937315 | 0.71 | MAPT (0.37) | SMN1; SMN2HTTMAPTMAPK1PKM | |
| SCHEMBL30804211 | 0.71 | MAPT (0.40) | TRPA1LMNAHTTALOX5TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 395 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025076059-A1 | ROCAGLATE DERIVATIVES AND USES THEREOF | TRUSTEES OF BOSTON UNIVERSITY (US) | 2025-04-10 | — | — | WO | claimed |
| US-12030992-B2 | Photocurable composition | CANON KABUSHIKI KAISHA (JP) | 2024-07-09 | — | — | US | claimed |
| CN-116589426-A | Method for synthesizing chiral 1, 3-benzoxazine derivative | 常州大学 | 2023-08-15 | — | — | CN | claimed |
| CN-116283815-B | Preparation method of 1, 3-benzoxazine compound | 嘉实（湖南）医药科技有限公司 | 2023-08-08 | — | — | CN | claimed |
| CN-116283815-A | Preparation method of 1, 3-benzoxazine compound | 嘉实（湖南）医药科技有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-111019646-B | Preparation and application of naphthalimide pyrrolo [2,1-b ] [1,3] benzoxazine derivative CN-probe | 湖北工业大学 | 2023-03-31 | — | — | CN | claimed |
| EP-4137543-A1 | COMPOSITION FOR PRODUCING A SHEET-LIKE SEMIFINISHED PRODUCT | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2023-02-22 | — | — | EP | claimed |
| EP-2606037-B1 | NOVEL COMPOSITIONS AND METHODS TO PRODUCE TRIAZINE-ARYLHYDROXY-ALDEHYDE CONDENSATES WITH IMPROVED SOLUBILITY | BAKELITE UK HOLDING LTD (GB) | 2022-05-25 | — | — | EP | claimed |
| CN-113106473-B | Method for preparing 1, 3-benzoxazine derivative through continuous electrochemical microreactor device | 南京工业大学 | 2022-02-18 | — | — | CN | claimed |
| CN-113106473-A | Method for preparing 1, 3-benzoxazine derivative through continuous electrochemical microreactor device | 南京工业大学 | 2021-07-13 | — | — | CN | claimed |
| CN-100358887-C | m-aminophenol derivatives and dyes containing these compounds | P & G CLAIROL INC (US) | 2008-01-02 | — | — | CN | claimed |
| US-6982263-B2 | Nitriles useful as reversible inhibitors of cysteine proteases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2006-01-03 | — | — | US | claimed |
| EP-1401443-A4 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORP (US) | 2005-10-26 | — | — | EP | claimed |
| US-6905590-B2 | Coating composition containing benzoxazine compound | NIPPON PAINT CO., LTD. (JP) | 2005-06-14 | — | — | US | claimed |
| EP-1401443-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-03-31 | — | — | EP | claimed |
| US-20030119827-A1 | Novel nitriles useful as reversible inhibitors of cysteine proteases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2003-06-26 | — | — | US | claimed |
| WO-2002100849-A2 | NOVEL NITRILES USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2002-12-19 | — | — | WO | claimed |
| WO-2002098424-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2002-12-12 | — | — | WO | claimed |
| EP-0477789-A1 | 1,3-Benzoxazine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1992-04-01 | — | — | EP | claimed |
| US-4895944-A | BACTERICIDE OFLOXACIN | DAIICHI SEIYAKU COMPANY, LTD. (JP) | 1990-01-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030119827-A1 | Novel nitriles useful as reversible inhibitors of cysteine proteases | NOS1, CTSK, CTSS | TRPA1 2949/4885ABCG2 2665/4885ITGB2 2669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.